The thioformimidate 4, which may be obtained by S-methylation of 5 reacts with chloroacetyl chloride/triethylamine to yield the trans-2-azetidinone 7. 7 is dehalogenated to 8.Removal of the protective group leads to 9, which undergoes ring closure by the
Ongania, Karl-Hans
p. 115 - 119
(2007/10/02)
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