Mechanism of the pinacol-pinacolone rearrangement of 2,3-di-(3-pyridyl)-2,3-butanediol in sulfuric acid
The reaction of 2,3-di-(3-pyridyl)-2,3-butanediol (1) in H2SO4 was studied. It was found that the meso and racemic forms give mono- and bis-SO3 addition products, which rearrange to a ketone (Metopirone) and two other majo