- COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
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The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, ARG, BCR-Abl, BRK, EphB, Fms, Fyn, KDR, c-Kit, LCK, PDGF-R, b-Raf, c-Raf, SAPK2, Src, Tie2 and TrkB kinases.
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Page/Page column 75
(2008/06/13)
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- Substituted triazolo[4,3-c]pyrimidines
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Substituted triazolo[4,3-c]pyrimidines which are bronchodilators. The pharmacological use of these compounds, and synthetic intermediates for the preparation of these compounds are also described.
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