100-88-9Relevant articles and documents
N-alkylated sulfamic acid derivatives as organocatalyst in multicomponent synthesis of fatty dihydropyrimidinones
Hack, Carolina R. L.,Porciuncula, Larissa,Weber, Andressa C. H.,D’Oca, Caroline R. M.,Russowsky, Dennis,Moura, Jaqueline M.,Pinto, Luiz A. A.,D’Oca, Marcelo G. M.
, p. 2342 - 2349 (2018)
In this work, N-alkylated sulfamic acid derivatives are introduced as promising acidic organocatalysts with convenient acidity and easy synthesis. The new organocatalysts derived from different nitrogenated compounds (amines, chitosan, urea and thiourea) were applied in multicomponent reactions to synthesize several dihydropyrimidinones (DHPMs). All tested organocatalysts resulted in good DHPM yields, using classic 1,3-dicarbonyl compounds and long-chain 1,3-dicarbonyl derivatives, demonstrating catalytic efficiency. N-Alkylated sulfamic acid derived from benzylamine showed good results (ca. 80percent yields). In addition, excellent results were obtained with organocatalysts based on sulfamic acid and thiourea (ca. 80-97percent yields), demonstrating the catalytic efficiency of new derivatives of thiourea organosulfamic catalysts.
Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds
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, (2008/06/13)
New condensed diazepinones of general formula I are described STR1 wherein B represents one of the divalent groups STR2 and X1, X2, A, R1 to R10 and Z are defined as in the specification.