| Conditions | Yield |
|---|
With
C26H36F6FeN6O6S2; C30H44N4O8; dihydrogen peroxide;Inwater; acetonitrile;at -30 ℃;
for 0.5h;
Reagent/catalyst;
enantioselective reaction; | 80%
|
With
sodium hypochlorite; chloro-<5,10,15,20-tetrakis<(1S,4R,5R,8S)-1,2,3,4,5,6,7,8-octahydro-1,4:5,8-dimethanoanthracene-9-yl>porphirinato>manganese(III); t-BuPy; tetradecyl benzyl dimethyl ammonium chloride;Indichloromethane;for 1h;
Product distribution;
Ambient temperature; | |
With
Oxone; C6H10O6(C3H4)2; tetra(n-butyl)ammonium hydrogensulfate; edetate disodium; sodium hydrogencarbonate;Inwater; acetonitrile;at -10 ℃;
for 1.5h;
Product distribution;
other reaction time, solvent, reagent; | |
With
Antifoam A; dihydrogen peroxide; sodium citrate;Inacetone;for 0.75h;
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
chloroperoxidase from the fungus Caldariomyces fumago; | |
With
lithium hypochlorite; benzyldimethyltetradecylammonium chloride; 1,5-dicyclohexyl imidazole;
chloromanganese porphyrin (C100H108N4)MnCl;Indichloromethane;at 0 - 5 ℃;
Title compound not separated from byproducts; | |
With
Oxone; AcOCH2C6H6O4(C3H6)2; potassium carbonate; acetic acid;In1,2-dimethoxyethane;at -10 ℃;
for 6h;
Yield given. Yields of byproduct given. Title compound not separated from byproducts; | |
With
N-methyl-2-indolinone; 3-chloro-benzenecarboperoxoic acid;
chiral salen Mn(III) complex immobilized on MCM41;Indichloromethane;at -78 ℃;
for 4h; | |
With
N-methyl-2-indolinone;
(S,S)-chloro[2,2'-[1,2-cyclohexanediylbis(nitrilomethylidyne)]bis-[4,6-bis(1,1-dimethylethyl)phenolato]](2-)-N,N',O,O'-manganese;Indichloromethane;at -78 ℃;
Title compound not separated from byproducts; | |
With
osmium(VIII) oxide; N-methyl-2-indolinone; quinine-based chiral ligand;Inwater; acetone;at 0 ℃;
for 10h;
Title compound not separated from byproducts; | |
With
sodium hypochlorite; chiral polystyrene-PhSO3-Mn(salen) derivative;Indichloromethane;at 20 ℃;
for 24h;
Further Variations:;
Reagents;
Product distribution; | |
With
sodium hypochlorite;
(S,S)-Mn(salen); silica gel;Indichloromethane;at 20 ℃;
for 24h;
pH=11.3;
Further Variations:;
Catalysts;
time;
Product distribution; | |
With
3-oxo-12α-(OCOCO2H)-5β-cholan-24-oic acid methyl ester; Oxone; sodium hydrogencarbonate;Inwater; acetonitrile;for 12h;
Title compound not separated from byproducts; | |
With
pyridine N-oxide; sodium hypochlorite; water;
salen-Mn(III);Indichloromethane;at 0 ℃;
for 10h;
Further Variations:;
Catalysts;
Temperatures;
Product distribution; | |
With
Di(2-ethylhexyl)phthalate; recombinant E. coli JM101 (pSPZ10); styrene monooxygenase; magnesium sulfate;Inoctane; water;at 30 ℃;
for 23.5h;
pH=7.1;
Title compound not separated from byproducts.;
Enzymatic reaction; | |
With
urea-hydrogen peroxide;In1,2-dichloro-ethane;at 40 ℃;
for 40h;
Title compound not separated from byproducts.; | |
With
oxone; ethylenediaminetetraacetic acid; C18H21NO6; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; acetic acid;In1,4-dioxane; water;at -10 ℃;
for 2h;
pH=9.3;
optical yield given as %ee; | |
With
C46H50Cl4Fe2N6O; dihydrogen peroxide; acetic acid;Inwater; acetonitrile;at 20 ℃;
for 0.05h;
optical yield given as %ee; | |
With
(5S,8R,9R)-2,2-dimethyl-10-oxo-1,3,6-trioxaspiro[4.5]decane-8,9-diyl diacetate; Oxone; ethylenediaminetetraacetic acid; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate;InDimethoxymethane; water; acetonitrile;at 0 ℃;
for 8h;
pH=7.0;
optical yield given as %ee;
aq. phosphate buffer; | |
With
Oxone; 18-crown-6 ether; C28H36N(1+)*F6Sb(1-); sodium hydrogencarbonate;Indichloromethane; water;at 0 ℃;
enantioselective reaction; | |
With
sodium hypochlorite; AuCl2((C6H5)(C3H3NO)(C5H3N)C(O)NCH(C6H5)CH2OH); oxygen;Indichloromethane;at 0 ℃;
for 6h;
pH=11;
aq. buffer; | |
With
potassium peroxomonosulfate; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; methyl 2-N-acetylamido-4,6-O-benzylidene-2-deoxy-3-ulose-α-D-ribo-hexapyranoside;Indiethylene glycol dimethyl ether; water; acetonitrile;at 20 ℃;
for 2.5h;
pH=10.6;
optical yield given as %ee;
aq. buffer; | |
With
(-)-chloro((1R,2R)-4,4',6,6'-tetra-tert-butyl-2,2'-[cyclohexane-1,2-diylbis(nitrilomethylidyne)]diphenolato)manganese(III);optical yield given as %ee;
enantioselective reaction;
Inert atmosphere; | |
With
3-chloro-benzenecarboperoxoic acid;Indichloromethane;at -78 ℃;
optical yield given as %ee;
enantioselective reaction; | |
With
Oxone; (1S,2R,5R)-ethyl 2',3-dioxo-8H-spiro[8-azabicyclo[3.2.1]octane-2,4'-[1,3]dioxolane]-8-carboxylate; sodium hydrogencarbonate;Inwater; acetonitrile;for 1.5h;
optical yield given as %ee;
enantioselective reaction; | |
With
Oxone; (1R,2R,5S)-ethyl 3'-methyl-2',3-dioxo-8H-spiro[8-azabicyco[3.2.1]octane-2,5'[1,3]oxazolidine]-8-carboxylate; sodium hydrogencarbonate;Inwater; acetonitrile;for 12.5h;
optical yield given as %ee;
enantioselective reaction; | |
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide;Indichloromethane;at 10 ℃;
for 24h; | |
With
peracetic acid; (S,S)-Mn(N,N′-bis(2-pyridylmethyl)-2,2′-bipyrrolidine);Inacetonitrile;at 0 ℃;
for 6h;
optical yield given as %ee;
enantioselective reaction; | |
With
sodium periodate;Intetrahydrofuran; dichloromethane; water;at 20 ℃;
for 24h;
optical yield given as %ee;
enantioselective reaction; | |
With
pyridine N-oxide; sodium hypochlorite; disodium hydrogenphosphate; 5,5-methylenedi-[(R,R)-{N-(3-tertbutylsalicylidine)-N'-(3'-tert-butyl-5'-(N,N-dibutylmethylene)salicyladhyde)}-1,2-cyclohexanediaminato(2-)manganese(III)chloride];Indichloromethane; water;at 0 ℃;
for 2.5h;
pH=11.3;
optical yield given as %ee;
enantioselective reaction; | |
With
ethylenediaminetetraacetic acid; Agrocybe aegerita aromatic peroxygenase; oxygen; Flavin mononucleotide;
at 20 ℃;
pH=7;
optical yield given as %ee;
enantiospecific reaction;
aq. phosphate buffer;
Irradiation;
Enzymatic reaction; | |
With
3C25H43NO2*H3O24PW4; dihydrogen peroxide;Inchloroform-d1; water;at 50 ℃;
for 48h;
optical yield given as %ee;
enantioselective reaction; | |
With
4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;Indichloromethane;at -20 ℃;
for 6h; | |
With
pyridine N-oxide; sodium hypochlorite;Indichloromethane;at 0 ℃;
for 0.5h;
optical yield given as %ee;
enantioselective reaction; | |
With
Agrocybe aegerita peroxygenase; dihydrogen peroxide;Inwater; acetonitrile;for 0.166667h;
pH=7;
enantioselective reaction;
potassium phosphate buffer;
Enzymatic reaction; | |
With
C24H32F3N3O4; dihydrogen peroxide;Intert-Amyl alcohol; acetonitrile;at 0 ℃;
for 6h;
optical yield given as %ee;
enantioselective reaction;
aq. buffer; | |
With
sodium hypochlorite; (-)-chloro((1R,2R)-4,4',6,6'-tetra-tert-butyl-2,2'-[cyclohexane-1,2-diylbis(nitrilomethylidyne)]diphenolato)manganese(III); 1-butyl-3-methylimidazolium Tetrafluoroborate;Inwater;at 0 ℃;
for 2h;
optical yield given as %ee;
enantioselective reaction; | |
isopropenylbenzene;With
Mn(1-(1-ethyl-1H-benzo[d]imidazol-2-yl)-N-((1-((1-ethyl-1H-benzo[d]imidazol-2-yl)methyl) pyrrolidin-2-yl)methyl)-N-methylmethanamine)(triflate)2; acetic acid;Inacetonitrile;for 0.0833333h;
Inert atmosphere; With
dihydrogen peroxide;Inacetonitrile;at -20 - 20 ℃;
for 2h;
enantioselective reaction;
Inert atmosphere; | |
With
sodium hypochlorite; disodium hydrogenphosphate; ammonium acetate;
at 0 ℃;
pH=11.3;
enantioselective reaction;
Ionic liquid; | |
With
sodium hypochlorite;Indichloromethane;at 0 ℃;
for 24h;
pH=11.5;
Reagent/catalyst;
enantioselective reaction; | 79.5 % ee
|
With
4-methylpyridine-1-oxide; sodium hypochlorite; C30H40ClMnN2O4;Indichloromethane;for 2h;
Reagent/catalyst;
enantioselective reaction; | 42.3 % ee
|
With
sodium hypochlorite; C10H13NO;Indichloromethane; water;at 0 ℃;
for 24h;
pH=11.3;
Overall yield = 58.7 %Chromat.; enantioselective reaction; | 89 % ee
|
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide; nonane; C52H75MnN7O2;Indichloromethane; water;at 25 ℃;
for 24h;
Optical yield = 91.6 %ee; | |
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide; C54H42ClMnN2O6;Indichloromethane;at 0 ℃;
Reagent/catalyst;
Temperature;
Overall yield = 92 %; enantioselective reaction; | 62 % ee
|
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide; C96H132Mn2N8O4;Indichloromethane; water;at 20 ℃;
for 6h;
pH=11.3;
Reagent/catalyst;
Temperature;
Time;
enantioselective reaction;
Catalytic behavior; | 89 % ee
|
With
sodium hypochlorite; C48H64ClMnN2O4;Inaq. phosphate buffer;at 15 ℃;
for 6h;
pH=11.3;
Reagent/catalyst;
Overall yield = 90 %; Optical yield = 87 %ee; enantioselective reaction;
Ionic liquid; | |
With
sodium hypochlorite; disodium hydrogenphosphate; C28H34ClMnN2O8S2(2-)*56H2O*40Zn(2+)*64HO(1-)*14NO3(1-); ammonium acetate;Indichloromethane;at 0 ℃;
for 6h;
Reagent/catalyst;
Catalytic behavior;
Cooling with ice; | 68 % ee
|
With
iodosylbenzene; C28H34ClMnN2O8S2(2-)*2Na(1+)*H2O; ammonium acetate;Indichloromethane;at 0 ℃;
for 6h;
Catalytic behavior; | 55 % ee
|
With
C52H76MnN7O2; 3-chloro-benzenecarboperoxoic acid;Indichloromethane;at -40 ℃;
for 5h;
Reagent/catalyst;
enantioselective reaction;
Catalytic behavior; | 89.6 % ee
|
With
pyridine N-oxide; C194H268Mn4N18O16; 3-chloro-benzenecarboperoxoic acid;Indichloromethane;at 0 ℃;
for 1h;
Overall yield = 66 %; enantioselective reaction;
Catalytic behavior; | 74 % ee
|
With
D-glucose;Inaq. phosphate buffer; ethanol;at 30 ℃;
for 5h;
pH=8;
Reagent/catalyst;
enantioselective reaction;
Enzymatic reaction; | 58.1 % ee
|
With
2-Ethylhexanoic acid; C26H36F6MnN6O6S2; dihydrogen peroxide;Inwater; acetonitrile;at -30 ℃;
for 1h;
Overall yield = 88 %Chromat.; Optical yield = 26 %ee; enantioselective reaction; | |
With
4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;
at 25 ℃;
for 4h;
Temperature;
Overall yield = 95 %Chromat.; Optical yield = 84.6 %ee; enantioselective reaction;
Catalytic behavior; | |
With
3-chloro-benzenecarboperoxoic acid;Intoluene;at -0.16 ℃;
for 6h;
Reagent/catalyst; | 78 % ee
|
With
4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;Indichloromethane;at -20 ℃;
Reagent/catalyst;
Optical yield = 87.6 %ee;
Catalytic behavior; | |
With
4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;Indichloromethane;at -20 ℃;
for 6h;
Reagent/catalyst;
Optical yield = 87.6 %ee; | |
With
4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;Indichloromethane;at -20 ℃;
for 6h;
Optical yield = 18 %ee; enantioselective reaction;
Catalytic behavior; | |
With
sodium hypochlorite; (-)-chloro((1R,2R)-4,4',6,6'-tetra-tert-butyl-2,2'-[cyclohexane-1,2-diylbis(nitrilomethylidyne)]diphenolato)manganese(III);Indichloromethane;at 0 ℃;
for 1h;
Reagent/catalyst;
Overall yield = 75 %;
Catalytic behavior; | 43 % ee
|
With
pyridine N-oxide; sodium hypochlorite;Indichloromethane;at 0 ℃;
for 1h;
pH=11.5;
Reagent/catalyst;
Overall yield = 91 %; enantioselective reaction;
Catalytic behavior; | 41 % ee
|
With
tert.-butylhydroperoxide; 4-methylmorpholine N-oxide;Indichloromethane;at 0 ℃;
for 6h;
Reagent/catalyst;
Temperature;
Solvent;
Overall yield = 98 %Chromat.; Optical yield = 80 %ee;
Catalytic behavior; | |
With
pyridine N-oxide; sodium chlorite; [(R,R)-(N,N-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminato)]manganese(III) chloride;Indichloromethane; water;at 0 ℃;
for 1h;
pH=11.5;
Reagent/catalyst;
Overall yield = 72 %; enantioselective reaction;
Catalytic behavior; | 45 % ee
|
With
pyridine N-oxide; sodium hypochlorite;Inwater;at 2 ℃;
for 0.5h;
Reagent/catalyst;
enantioselective reaction;
Catalytic behavior; | 75 % ee
|
With
tert.-butylhydroperoxide; 5Ni(2+)*1.4C3H7NO*9H2O*2C48H28N4O8(2-);Inacetonitrile;at 80 ℃;
Overall yield = 66 %; Optical yield = 85 %ee; regioselective reaction;
Sealed tube; | |
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide;Indichloromethane;at 20 ℃;
for 24h;
pH=11.5;
Reagent/catalyst;
Temperature;
enantioselective reaction;
Catalytic behavior; | 88 % ee
|
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide;Indichloromethane;at 20 ℃;
for 24h;
pH=11.5;
Reagent/catalyst;
Optical yield = 88 %ee; enantioselective reaction;
Catalytic behavior; | |
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide; (-)-chloro((1R,2R)-4,4',6,6'-tetra-tert-butyl-2,2'-[cyclohexane-1,2-diylbis(nitrilomethylidyne)]diphenolato)manganese(III);Indichloromethane;for 2h;
Reagent/catalyst;
enantioselective reaction;
Catalytic behavior; | 65 % ee
|
With
tert.-butylhydroperoxide; P450 peroxygenase T213M mutant;Inaq. phosphate buffer;at 35 ℃;
for 0.166667h;
pH=7.5;
Reagent/catalyst;
enantioselective reaction;
Enzymatic reaction; | 63.2 % ee
|
With
4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;Indichloromethane;at 0 ℃;
enantioselective reaction; | 82 % ee
|
With
1H-imidazole; sodium periodate; C49H71MnN4O2;Inwater; acetonitrile;for 5h;
Catalytic behavior; | 82 % ee
|
With
(-)-chloro((1R,2R)-4,4',6,6'-tetra-tert-butyl-2,2'-[cyclohexane-1,2-diylbis(nitrilomethylidyne)]diphenolato)manganese(III); 4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;Indichloromethane;at 0 ℃;
Reagent/catalyst;
enantioselective reaction;
Catalytic behavior; | 52 % ee
|
With
sodium periodate; C49H73MnN4O2;Indichloromethane;at -20 ℃;
Reagent/catalyst;
enantioselective reaction;
Catalytic behavior; | 82 % ee
|
With
tert.-butylhydroperoxide; quadruple-mutant S148P/I161T/K199E/T214V Sulfolobus acidocaldarius CYP119 peroxygenase;Inaq. phosphate buffer;at 35 ℃;
for 0.166667h;
pH=7.5;
Reagent/catalyst;
enantioselective reaction;
Enzymatic reaction; | 22.9 % ee
|
With
oxygen; isobutyraldehyde;Inacetonitrile;at 60 ℃;
for 2h;
under 750.075 Torr;
enantioselective reaction; | 76 %Chromat.
20 %Chromat.
|
With
C108H136Mn2N4O8; 4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;Indichloromethane;at 0 ℃;
for 1h;
Reagent/catalyst;
enantioselective reaction; | 79.5% ee
|
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide;Indichloromethane; water;at 25 ℃;
for 24h;
pH=11.3;
Reagent/catalyst;
Catalytic behavior; | 89 % ee
|
With
iodosylbenzene; C44H36ClF18FeN2O2;Inacetonitrile;at 23 ℃;
for 12h;
Optical yield = 48 %ee; enantioselective reaction; | |
With
(-)-chloro((1R,2R)-4,4',6,6'-tetra-tert-butyl-2,2'-[cyclohexane-1,2-diylbis(nitrilomethylidyne)]diphenolato)manganese(III); 4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;Innonane; dichloromethane;for 1h;
Reagent/catalyst;
Catalytic behavior; | 54 % ee
|
With
tert.-butylhydroperoxide;Inwater; 1,2-dichloro-ethane;at 80 ℃;
for 4h;
enantioselective reaction;
Catalytic behavior; | 83 % ee
|
With
(S)-N-((R)-3,3-dimethylbutan-2-yl)-3,3-dimethyl-2-(((1-methyl-1H-imidazol-2-yl)methyl)amino)butanamide; iron(III) chloride hexahydrate; dihydrogen peroxide;Intert-Amyl alcohol; water;at 20 ℃;
for 1h;
Overall yield = 22 percentSpectr.; enantioselective reaction; | 16 % ee
|
With
3C8H4O4(2-)*O(2-)*3Cr(3+)*C4H5O6(1-); oxygen; isobutyraldehyde;Inacetonitrile;at 80 ℃;
for 8h;
under 760.051 Torr;
enantioselective reaction; | 85 % ee
|
With
iodosylbenzene; ammonium acetate;Indichloromethane;at -0.16 ℃;
for 6h;
Reagent/catalyst;
enantioselective reaction;
Catalytic behavior; | 51 % ee
|
With
oxygen; isobutyraldehyde;Inethyl acetate;at 60 ℃;
for 8h;
under 750.075 Torr;
enantioselective reaction; | 89 % ee
|
With
1-Benzyl-1,4-dihydronicotinamide; styrene monooxygenase from Sphingopyxis fribergensis Kp5.2; flavin adenine dinucleotide; catalase from bovine liver;Indimethyl sulfoxide;at 30 ℃;
for 1h;
pH=7;
enantioselective reaction;
Catalytic behavior;
Enzymatic reaction; | 89 % ee
|
With
pyridine N-oxide; sodium hypochlorite;Indichloromethane;at 0 ℃;
for 0.666667h;
enantioselective reaction; | 39 % ee
|
All total 106 Articles be found
All total 106 Articles be found
