1000304-38-0 Usage
Uses
Used in Pharmaceutical Research and Development:
(1R,2R,3S,4R,5R)-2-TERT-BUTOXY-CARBONYLAMINO-4,6,6-TRIMETHYLBI-CYCLO[3.1.1]HEPTANE-3-CARBOXYLIC ACID is used as a key intermediate in the synthesis of pharmaceutical compounds due to its unique bicyclic structure and multiple chiral centers. Its potential as a precursor for the development of new drugs with specific biological activities makes it a valuable asset in medicinal chemistry.
Used in Organic Synthesis:
In the field of organic synthesis, (1R,2R,3S,4R,5R)-2-TERT-BUTOXY-CARBONYLAMINO-4,6,6-TRIMETHYLBI-CYCLO[3.1.1]HEPTANE-3-CARBOXYLIC ACID serves as a building block for the creation of novel biologically active compounds. Its structural complexity and the presence of various functional groups allow for a wide range of chemical reactions, facilitating the synthesis of diverse organic molecules with potential applications in various industries.
Used as a Protecting Group in Organic Synthesis:
The tert-butoxy-carbonylamino group in (1R,2R,3S,4R,5R)-2-TERT-BUTOXY-CARBONYLAMINO-4,6,6-TRIMETHYLBI-CYCLO[3.1.1]HEPTANE-3-CARBOXYLIC ACID can be employed as a protecting group in organic synthesis. This allows chemists to selectively modify other functional groups in a molecule without affecting the carboxylic acid or other reactive sites, which is crucial for the synthesis of complex organic compounds with specific desired properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1000304-38-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,3,0 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1000304-38:
(9*1)+(8*0)+(7*0)+(6*0)+(5*3)+(4*0)+(3*4)+(2*3)+(1*8)=50
50 % 10 = 0
So 1000304-38-0 is a valid CAS Registry Number.
1000304-38-0Relevant articles and documents
Regio- and stereoselective synthesis of the enantiomers of monoterpene-based β-amino acid derivatives
Szakonyi, Zsolt,Martinek, Tamas A.,Sillanpaeae, Reijo,Fueloep, Ferenc
, p. 2442 - 2447 (2008/03/13)
The regio- and stereospecific addition of chlorosulfonyl isocyanate to cis-δ-pinene enantiomers has furnished monoterpene-fused β-lactams. The observed regioselectivity can be explained by ab initio DFT modeling of transition state structures. In contrast with the less reactive α-pinane-fused β-lactam 4, the resulting β-lactams 5 and 13 containing an amino group connected to a secondary carbon possess similar reactivity to the cycloalkane-fused analogues and can be easily converted to the β-amino acid and its protected derivatives. The base-catalyzed isomerization of the cis-amino ester afforded the corresponding trans-amino ester in moderate yield.
