1000341-14-9 Usage
Description
3-IODO-4-TRIFLUROMETHYL (1H)INDAZOLE is a chemical compound belonging to the indazole family, characterized by the presence of an iodine atom at the 3rd position and a trifluoromethyl group at the 4th position. It is a versatile intermediate in the synthesis of various indazole derivatives, which have potential applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
3-IODO-4-TRIFLUROMETHYL (1H)INDAZOLE is used as a reactant for the preparation of indazole derivatives, specifically as CRTH2 antagonists. These derivatives have potential applications in the treatment of various inflammatory and allergic diseases, such as asthma and allergic rhinitis, by targeting the chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2).
Check Digit Verification of cas no
The CAS Registry Mumber 1000341-14-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,3,4 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1000341-14:
(9*1)+(8*0)+(7*0)+(6*0)+(5*3)+(4*4)+(3*1)+(2*1)+(1*4)=49
49 % 10 = 9
So 1000341-14-9 is a valid CAS Registry Number.
1000341-14-9Relevant articles and documents
New CRTh2 antagonists.
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Paragraph 0209, (2013/03/26)
The present invention relates to compounds of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by CRTh2 antagonist activity.
