1000342-93-7

Basic information

• Product Name: 1H-Indole, 4-broMo-6-(trifluoroMethyl)-
• Synonyms: 1H-Indole, 4-broMo-6-(trifluoroMethyl)-;4-broMo-6-trifluoroMethyl-1H indole
• CAS NO: 1000342-93-7
• Molecular Formula: C9H5BrF3N
• Molecular Weight: 264.0419096
• Mol File: 1000342-93-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 298.1±35.0 °C(Predicted)
• Appearance: /
• Density: 1.742±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.66±0.30(Predicted)
• CAS DataBase Reference: 1H-Indole, 4-broMo-6-(trifluoroMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 4-broMo-6-(trifluoroMethyl)-(1000342-93-7)
• EPA Substance Registry System: 1H-Indole, 4-broMo-6-(trifluoroMethyl)-(1000342-93-7)

Safety Data

• Hazardous Substances Data: 1000342-93-7(Hazardous Substances Data)

Usage

General Description

"1H-Indole, 4-bromo-6-(trifluoromethyl)-" is a specific type of organic compound that belongs to the family of indoles. The indoles are organic compounds featuring a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. In this particular compound, a bromine atom is attached at the fourth position and a trifluoromethyl group (-CF3) is attached at the sixth position of the indole structure. It is classified as a halogenated indole and is typically used in chemical research due to its unique reactivity related to the presence of both the halogen and the highly electronegative trifluoromethyl group. This makes it useful in the synthesis of more complex chemical structures.

Upstream product

• 1100215-56-2 3-bromo-5-(trifluoromethyl)-2-((trimethylsilyl)ethynyl)aniline 
• 1100215-54-0 3-bromo-2-iodo-5-(trifluoromethyl)aniline 
• 54962-75-3 [3-bromo-5-(trifluoromethyl)phenyl]amine 
• 1100215-58-4 3-bromo-2-ethynyl-5-(trifluoromethyl)aniline 

Downstream Products

• 1100215-61-9 6-(trifluoromethyl)-1H-indole-4-carbaldehyde 

Relevant articles and documents

NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF

An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. Th e present invention provides a nicotinamide derivative represented by the follo wing formula (I) (wherein R 1 represents a halogen atom; R 2 represents a C 1-12 alkyl group, a C 2-12 alkenyl group, a C 2-12 alkynyl group, a C 3-8 cycloalkyl g roup, an aryl group, an ar-C 1-6 alkyl group or a heterocyclic group, each opti onally having at least one substituent; R 3 represents an aryl group or a hetero cyclic group each optionally having at least one substituent; and R 4 and R 5 e ach independently represent a hydrogen atom; and R 2 and R 4 may form a cyc lic amino group optionally having at least one substituent together with the ni trogen atom to which they bind) or a salt thereof, and a pharmaceutical comp osition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.

HETEROCYCLIC COMPOUND

The present invention provides a compound or a salt thereof useful for an agent for the prophylaxis or treatment of neurodegenerative disease and the like. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.