100036-01-9

Basic information

• Product Name: ethyl 2,3-dichloro-3-phenylpropanoate
• CAS NO: 100036-01-9
• Molecular Weight: 247.121
• Mol File: 100036-01-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ethyl 2,3-dichloro-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2,3-dichloro-3-phenylpropanoate(100036-01-9)
• EPA Substance Registry System: ethyl 2,3-dichloro-3-phenylpropanoate(100036-01-9)

Safety Data

• Hazardous Substances Data: 100036-01-9(Hazardous Substances Data)

Upstream product

• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 4192-77-2 ethyl cinnamate 
• 64-17-5 ethanol 
• 35115-76-5 2,3-dichloro-3-phenyl-propionic acid 

Downstream Products

• 84033-37-4 (2R,3S)-1-((Z)-2-Ethoxycarbonyl-vinyl)-3-phenyl-aziridine-2-carboxylic acid ethyl ester 
• 84033-37-4 (2S,3S)-1-((E)-2-Ethoxycarbonyl-vinyl)-3-phenyl-aziridine-2-carboxylic acid ethyl ester 
• 84033-38-5 (Z)-2-((2S,3R)-2-Ethoxycarbonyl-3-phenyl-aziridin-1-yl)-but-2-enedioic acid dimethyl ester 
• 84033-38-5 (E)-2-((2S,3R)-2-Ethoxycarbonyl-3-phenyl-aziridin-1-yl)-but-2-enedioic acid dimethyl ester 
• 66051-35-2 ethyl (E)-2-chloro-3-phenyl-2-propenoate 
• 66051-36-3 ethyl (Z)-2-chloro-3-phenyl-2-propenoate 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 84024-60-2 trans-3-phenylaziridine-2-carboxylic acid ethyl ester 
• 84024-60-2 cis 3-phenylaziridine-2-carboxylic acid ethyl ester 
• 26880-33-1 ethyl 2-chloro-3-phenylacrylate 

Relevant articles and documents

Convenient chlorination with concentrated hydrochloric acid in the presence of iodosylbenzene

An efficient chlorination of -keto esters, 1,3-diketones, and alkenes was performed conveniently with concentrated HCl in the presence of PhIO, selectively giving -chloro - keto esters, 2-chloro-1,3-diketones, and 1,2-dichloroalkanes, respectively. It was suggested that the chlorination took place with (dichloroiodo)benzene generated in situ. A selective anti-addition was observed in the chlorination of indene. Georg Thieme Verlag Stuttgart New York.

Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand

Chlorination with chlorine is straightforward, highly reactive, and versatile, but it has significant limitations. In this Letter, we introduce a protocol that could combine the efficiency of electrochemical transformation and the high reactivity of chlorine. By utilizing Cl3CCN as the chloride source, donating up to all three chloride atom, the reaction could generate and consume the chlorine in situ on demand to achieve the chlorination of aromatic compounds and electrodeficient alkenes.

Preparation and oxidation of α-phenylselanyl esters

Alkylation and selenenylation of selenium-stabilized ester enolates have allowed the preparation of α-phenylselanyl esters 5, 7, 8 and of α,α-bis(phenylselanyl)esters 6, respectively. The competitive selenophilic reaction, leading to an allylic phenylselenide 9, was avoided in the presence of HMPA. α-phenylselanyl α,β-unsaturated esters 15 were prepared by oxidation of compounds 6 and dehydrohalogenation of β-chloroesters 17. Some other transformations: oxidation, transesterification and Grignard reaction were also studied. H2O2 oxidation of Z-esters 15 has led to stable E-α-seleninyl esters 20. (C) 2000 Elsevier Science Ltd.