1000576-51-1 Usage
Description
3-cyano-1H-Indole-6-carboxylic acid methyl ester is a chemical compound characterized by the molecular formula C13H10N2O2. It is a methyl ester derivative of 3-cyano-1H-indole-6-carboxylic acid, known for its potential biological activities and versatility in organic synthesis and pharmaceutical research. 3-cyano-1H-Indole-6-carboxylic acid methyl ester is recognized for its potential as a building block in drug development, as well as its utility as a reagent in chemical reactions and a precursor for synthesizing biologically active molecules.
Uses
Used in Pharmaceutical Research:
3-cyano-1H-Indole-6-carboxylic acid methyl ester is used as a building block in drug development for its potential to contribute to the creation of new pharmaceuticals. Its unique structure allows it to be a key component in the synthesis of various biologically active molecules, which can be further explored for therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 3-cyano-1H-Indole-6-carboxylic acid methyl ester serves as a reagent in chemical reactions. Its properties make it a valuable intermediate for the synthesis of a range of organic compounds, facilitating the development of new chemical entities with potential applications across various industries.
Used in Chemical Reactions as a Precursor:
3-cyano-1H-Indole-6-carboxylic acid methyl ester is utilized as a precursor in the synthesis of various biologically active molecules. Its role in these reactions is crucial for the production of compounds that may exhibit significant biological activity, thus contributing to the advancement of medicinal chemistry and the discovery of new therapeutic agents.
Used in Research and Development:
3-cyano-1H-Indole-6-carboxylic acid methyl ester is employed in research and development settings to explore its potential applications and properties further. Its versatility and the possibility of modification make it an attractive candidate for studies aimed at understanding its interactions with biological systems and its potential role in the development of new drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1000576-51-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,5,7 and 6 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1000576-51:
(9*1)+(8*0)+(7*0)+(6*0)+(5*5)+(4*7)+(3*6)+(2*5)+(1*1)=91
91 % 10 = 1
So 1000576-51-1 is a valid CAS Registry Number.
1000576-51-1Relevant articles and documents
Discovery of N-(4′-(indol-2-yl)phenyl)sulfonamides as novel inhibitors of HCV replication
Chen, Guangming,Ren, Hongyu,Turpoff, Anthony,Arefolov, Alexander,Wilde, Richard,Takasugi, James,Khan, Atiyya,Almstead, Neil,Gu, Zhengxian,Komatsu, Takashi,Freund, Connie,Breslin, Jamie,Colacino, Joseph,Hedrick, Jean,Weetall, Marla,Karp, Gary M.
, p. 3942 - 3946 (2013/07/27)
A series of novel 2-phenylindole analogs were synthesized and evaluated for activity in subgenomic HCV replicon inhibition assays. Several compounds containing small alkyl sulfonamides on the phenyl ring exhibiting submicromolar EC50 values against the genotype 1b replicon were identified. Among these, compound 25d potently inhibited the 1b replicon (EC50 = 0.17 μM) with 147-fold selectivity with respect to cytotoxicity. Compound 25d was stable in the presence of human liver microsomes and had a good pharmacokinetic profile in rats with an IV half-life of 4.3 h and oral bioavailability (F) of 58%.
