100068-46-0

Basic information

• Product Name: 3',4'-DIHYDRO-SPIRO[CYCLOHEXANE-1,1'(2'H)-PYRIDO[3,4-B]INDOLE]-3'-CARBOXYLIC ACID
• Synonyms: ASINEX-REAG BAS 12311061;3',4'-DIHYDRO-SPIRO[CYCLOHEXANE-1,1'(2'H)-PYRIDO[3,4-B]INDOLE]-3'-CARBOXYLIC ACID;TIMTEC-BB SBB012244
• CAS NO: 100068-46-0
• Molecular Formula: C17H20N2O2
• Molecular Weight: 284.35
• Mol File: 100068-46-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3',4'-DIHYDRO-SPIRO[CYCLOHEXANE-1,1'(2'H)-PYRIDO[3,4-B]INDOLE]-3'-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3',4'-DIHYDRO-SPIRO[CYCLOHEXANE-1,1'(2'H)-PYRIDO[3,4-B]INDOLE]-3'-CARBOXYLIC ACID(100068-46-0)
• EPA Substance Registry System: 3',4'-DIHYDRO-SPIRO[CYCLOHEXANE-1,1'(2'H)-PYRIDO[3,4-B]INDOLE]-3'-CARBOXYLIC ACID(100068-46-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 100068-46-0(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 73-22-3 L-Tryptophan 
• 54-12-6 Trp 

Relevant articles and documents

Design, synthesis, and biological evaluation of 2-substituted-2,3,4,9-tetrahydrospiro-β-carboline-3-carboxylic acid derivatives as first-in-class mast cell stabilizers

Mast cell degranulation plays a momentous role in myriad diseases like asthma, eczema, allergic rhinitis, and conjunctivitis as well as anaphylactic shock; hence, there is an unmet need for developing new mast cells stabilizers. The reported mast cell sta

Pictet-Spengler Reactions of Tryptamine and Tryptophan with Cycloalkanones and Ketonic Mannich Bases

A Pictet-Spengler reaction of tryptamine (1) with cyclopentanone under physiological conditions gave 3-(cyclopentylideneaminoethyl)indole (3), which was cyclized to the 1-spirocyclic 1,2,3,4-tetrahydro-2-carboline (4).Treatment of (+/-)-tryptophan with cy