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  • Manufacture/Brand
  • Product Description
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  • Manufacture/Brand:TRC
  • Product Description:De(carboxymethoxy)CetirizineAceticAcidDihydrochloride
  • Packaging:50mg
  • Price:$ 155
  • Delivery:In stock
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Relevant articles and documentsAll total 1 Articles be found

Glycine transporter-1 inhibitors


Page/Page column 31, (2008/06/13)

The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of GlyT1 such as cognitive disorders associated with Schizophrenia, ADHD (attention deficit hyperactivity disorder), MCI (mild cognitive impairment), and the like. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Process route upstream and downstream products

Process route

tert-butyl 2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetate

tert-butyl 2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetate

2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid dihydrochloride salt

2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid dihydrochloride salt

Conditions Yield
With hydrogenchloride; water; In 1,4-dioxane; at 50 ℃; for 6h;

Global suppliers and manufacturers

Global( 5) Suppliers
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  • Topbatt Chemical Co., Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:13828841343
  • Emails:ivywang@topbatt.net
  • Main Products:1
  • Country:China (Mainland)
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