100074-51-9

Basic information

• Product Name: 3-Biphenyl-4-yl-4-hydroxy-5H-furan-2-one
• Synonyms: 3-Biphenyl-4-yl-4-hydroxy-5H-furan-2-one
• CAS NO: 100074-51-9
• Molecular Weight: 252.269
• Mol File: 100074-51-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Biphenyl-4-yl-4-hydroxy-5H-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Biphenyl-4-yl-4-hydroxy-5H-furan-2-one(100074-51-9)
• EPA Substance Registry System: 3-Biphenyl-4-yl-4-hydroxy-5H-furan-2-one(100074-51-9)

Safety Data

• Hazardous Substances Data: 100074-51-9(Hazardous Substances Data)

Upstream product

• 86540-09-2 Biphenyl-4-yl-acetic acid ethoxycarbonylmethyl ester 
• 98026-98-3 3-Diazotetrahydrofuran-2,4-dione 
• 92-52-4 biphenyl 
• 5728-52-9 (4-biphenylyl)acetic acid 

Downstream Products

• 100093-04-7 3-Biphenyl-4-yl-5-bromo-4-methoxy-5H-furan-2-one 
• 100074-64-4 3-[1,1'-biphenyl]-4-yl-4-methoxy-5H-furan-2-one 

Relevant articles and documents

Catalytic Undirected Intermolecular C-H Functionalization of Arenes with 3-Diazofuran-2,4-dione: Synthesis of 3-Aryl Tetronic Acids, Vulpinic Acid, Pinastric Acid, and Methyl Isoxerocomate

A variety of 3-aryl tetronic acids have been synthesized by an undirected, intermolecular C-H functionalization of arenes with 3-diazofuran-2,4-dione. This methodology featured as a key step in the synthesis of a series of naturally occurring 3-aryl-5-arylidene tetronic acids (pulvinates) from commercially available tetronic acid. Salient features of the pulvinic acid synthesis include a one-step, stereoselective synthesis of the C5 arylidene group and a single step introduction of the C3 aryl substituent.