100074-57-5

Basic information

• Product Name: 2(5H)-Furanone, 3-(2-fluorophenyl)-4-methoxy-
• CAS NO: 100074-57-5
• Molecular Formula: C11H9FO3
• Molecular Weight: 208.189
• Mol File: 100074-57-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 3-(2-fluorophenyl)-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 3-(2-fluorophenyl)-4-methoxy-(100074-57-5)
• EPA Substance Registry System: 2(5H)-Furanone, 3-(2-fluorophenyl)-4-methoxy-(100074-57-5)

Safety Data

• Hazardous Substances Data: 100074-57-5(Hazardous Substances Data)

Upstream product

• 451-82-1 (2-fluorophenyl)acetic acid 
• 69556-70-3 4-methoxy-5H-furan-2-one 
• 71387-05-8 4-methoxy-3-bromo-furan-2(5H)-one 
• 1993-03-9 o-fluorophenylboronic acid 
• 100074-44-0 3-(2-fluorophenyl)-4-hydroxyfuran-2(5H)-one 
• 77-78-1 dimethyl sulfate 
• 100074-31-5 (2-Fluoro-phenyl)-acetic acid ethoxycarbonylmethyl ester 

Downstream Products

• 100074-70-2 5-Bromo-3-(2-fluoro-phenyl)-4-methoxy-5H-furan-2-one 

Relevant articles and documents

Compound, as well as preparation method and application thereof

The application discloses a compound of which the structure is represented as the following formula, wherein R1 is selected from any one of F, Cl, Br, C1-C5 alkyl group, and a group having the structure as the formula (1), n = 0, 1, 2, 3, 4 or 5; the R2 is selected from any one of a group having the structure as the formula (1), a group having the structure as the formula (2), and a group having the structure as the formula (3). The compound has simple preparation method, can be used as a neuraminidase inhibitor, and has excellent antivirus activity.

Synthesis of (E)- and (Z)-Pulvinones

Two new routes to pulvinones have been developed, one of which involves a novel Wittig reaction.For the first time, members of the E-series, including the parent (E)-pulvinone, are reported and the structural elucidation of the geometric isomers is descri