1000894-45-0 Usage
Molecular weight
313.39 g/mol
Structure
The compound consists of a piperazine ring attached to a phenoxyacetic acid group through an oxygen atom. The phenoxyacetic acid group has a 4-(tert-butoxycarbonyl) substituent.
Functional groups
The compound contains a piperazine ring, a phenoxyacetic acid group, and a tert-butoxycarbonyl (Boc) protecting group.
Physical properties
The physical properties of the compound are not provided in the material.
Chemical properties
+ The Boc protecting group can be removed under acidic or basic conditions to reveal a free amine group.
+ The compound may undergo reactions that affect the phenoxyacetic acid group or the piperazine ring, such as esterification or amidation.
Biological activity
The biological activity of the compound is not provided in the material, but it is mentioned that the phenoxyacetic acid group can provide biological activity.
Potential pharmacological applications
The compound may have potential use in medicinal chemistry for the development of pharmaceuticals targeting various biological pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 1000894-45-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,8,9 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1000894-45:
(9*1)+(8*0)+(7*0)+(6*0)+(5*8)+(4*9)+(3*4)+(2*4)+(1*5)=110
110 % 10 = 0
So 1000894-45-0 is a valid CAS Registry Number.
1000894-45-0Relevant articles and documents
Substituted Piperidines that Increase P53 Activity and the Uses Thereof
-
Page/Page column 78, (2008/06/13)
In its many embodiments, the present invention discloses novel compounds, as inhibitors of HDM2 protein, methods for preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of treatment, prevention, inhibition, of one or more diseases associated with the HDM2 protein or P53 using such compounds or pharmaceutical compositions.
