100097-67-4

Basic information

• Product Name: 1,2,3-Thiadiazole-4-carbothioamide,5-amino-N-methyl-(9CI)
• Synonyms: 1,2,3-Thiadiazole-4-carbothioamide,5-amino-N-methyl-(9CI)
• CAS NO: 100097-67-4
• Molecular Formula: C4H6N4S2
• Molecular Weight: 174.24724
• Product Categories: THIOAMIDE
• Mol File: 100097-67-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,3-Thiadiazole-4-carbothioamide,5-amino-N-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-Thiadiazole-4-carbothioamide,5-amino-N-methyl-(9CI)(100097-67-4)
• EPA Substance Registry System: 1,2,3-Thiadiazole-4-carbothioamide,5-amino-N-methyl-(9CI)(100097-67-4)

Safety Data

• Hazardous Substances Data: 100097-67-4(Hazardous Substances Data)

Usage

Structure

1,2,3-Thiadiazole ring with a carbothioamide group and an amino group with a methyl substituent

Derivative of

1,2,3-Thiadiazole

Pharmacological activities

Antimicrobial, antifungal, and antitumor properties

Applications

a. Building block in organic synthesis for the preparation of various bioactive molecules
b. Potential corrosion inhibitor
c. Intermediate in the production of veterinary drugs and agricultural chemicals

Upstream product

• 117971-49-0 5-(N-methylamino)-1,2,3-thiadiazole-4-carbonitrile 
• 100097-70-9 5-amino-4-N-methylcarbamoyl-1,2,3-thiadiazole 
• 121511-85-1 5-amino-1,2,3-thiadiazole-4-N-methylthiocarboxamide 
• 126739-85-3 N-Methyl-dithiomalonamide 
• 100097-71-0 5-Mercapto-1H-1,2,3-triazole-4-N-methylcarboxamide 
• 91679-52-6 2-Diazo-2-cyanoacetic acid N-methylamide 

Downstream Products

• 100097-69-6 1-N-methyl-5-mercapto-1,2,3-triazole-4-carbothioamide 

Relevant articles and documents

STUDY OF THE CHARACTERISTICS OF REARRANGEMENTS OF 5-AMINO-1,2,3-THIADIAZOLE-4-CARBOTHIOAMIDES

Using NMR spectroscopy, we have determined the relative stability and the effect of the solvent on the ratio of isomeric N,N-disubstituted 5-amino-1,2,3-thiadiazole-4-carbothioamides in a mixture.We carried out chromatographic separation of a mixture of 5

STUDY OF DIRECTION OF CYCLIZATION OF MALONODITHIOAMIDES AS A METHOD OF INVESTIGATION OF REACTIVITY OF α-DIAZOTHIOACETAMIDES

The reaction of malonothioamides with benzene-sulfonyl azide and 2-azido-3-ethylbenzthiazolium tatrafluoroborate gave amides of 2-diazothiomalonic acid, which underwent cyclization to a mixture of 5-N-R-amino-1,2,3-thiadiazole-4-carbothioamides and 5-amin

Reaction of 5-mercapto-1,2,3-triazole-4-carboxamides with phosphorus decasulfide

The reaction of 5-mercapto-1,2,3-triazole-4-carboxamide with P4S10 was studied; the mechanism of this reaction is discussed. The effect of the donor-acceptor properties of the substituents on the direction of cyclization of the intermediate malonic acid α-diazodithioamide was investigated. A new rearrangement in the 5-mercapto-1,2,3-triazole series was observed.

HETEROCYCLIZATION OF COMPOUNDS CONTAINING DIAZO AND CYANO GROUPS. 4. REACTIONS OF 2-DIAZO-2-CYANOACETIC ACID AMIDES WITH P4S10 AND THE LAWESSON REAGENT. SYNTHESIS AND RECYCLIZATION OF 5-AMINO-1,2,3-THIADIAZOLE-4-CARBOTHIOAMIDES

5-Amino-1,2,3-thiadiazole-4-carbothioamides were obtained in the reaction of carbonyl derivatives of diazoacetonitrile with P4S10 and the Lawesson reagent.A novel recyclization of 1,2,3-thiadiazole-4-carbothioamides was observed.