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1H-Pyrazole-4-carboxaldehyde, 3-(trifluoromethyl)is a chemical compound characterized by the molecular formula C6H4F3N3O. It is an aldehyde derivative of the five-membered aromatic heterocyclic compound, pyrazole. The distinctive feature of 1H-Pyrazole-4-carboxaldehyde, 3-(trifluoromethyl)- is the presence of a trifluoromethyl group at the 3-position of the pyrazole ring, which significantly influences its reactivity and properties. This makes 1H-Pyrazole-4-carboxaldehyde, 3-(trifluoromethyl)a valuable building block in the realm of organic synthesis, particularly within the pharmaceutical industry. Its potential as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, along with its intriguing properties, positions it as a promising candidate for further research and development in medicinal chemistry and material science.

1001020-14-9

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1001020-14-9 Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrazole-4-carboxaldehyde, 3-(trifluoromethyl)is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into complex molecular structures, enhancing the potency and selectivity of the resulting drugs. The trifluoromethyl group imparts unique properties to the molecules, such as increased lipophilicity and metabolic stability, which are beneficial for drug development.
Used in Agrochemical Industry:
In the agrochemical sector, 1H-Pyrazole-4-carboxaldehyde, 3-(trifluoromethyl)serves as a crucial intermediate in the creation of novel agrochemicals. Its incorporation into these compounds can lead to improved effectiveness against pests and diseases, as well as enhanced environmental stability due to the electron-withdrawing nature of the trifluoromethyl group.
Used in Medicinal Chemistry Research:
1H-Pyrazole-4-carboxaldehyde, 3-(trifluoromethyl)is utilized as a starting material in medicinal chemistry research to explore its potential in the development of new therapeutic agents. Its unique structural features allow for the design and synthesis of compounds with specific biological activities, such as anti-inflammatory, antimicrobial, or anticancer properties.
Used in Material Science:
1H-Pyrazole-4-carboxaldehyde, 3-(trifluoromethyl)also finds application in material science, where its properties are harnessed to develop new materials with specialized characteristics. For instance, the trifluoromethyl group can influence the electronic properties of materials, making them suitable for applications in sensors, electronic devices, or as components in advanced composites.

Check Digit Verification of cas no

The CAS Registry Mumber 1001020-14-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,1,0,2 and 0 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1001020-14:
(9*1)+(8*0)+(7*0)+(6*1)+(5*0)+(4*2)+(3*0)+(2*1)+(1*4)=29
29 % 10 = 9
So 1001020-14-9 is a valid CAS Registry Number.

1001020-14-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(Trifluoromethyl)-1H-pyrazole-4-carbaldehyde

1.2 Other means of identification

Product number -
Other names 5-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1001020-14-9 SDS

1001020-14-9Downstream Products

1001020-14-9Relevant articles and documents

SUBSTITUTED BICYCLE HETEROCYCLIC DERIVATIVES USEFUL AS ROMK CHANNEL INHIBITORS

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Page/Page column 105; 106; 174, (2018/06/06)

Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is (II) or (III); each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3, L1, L2, R1a, R1b, R1c, and n are define herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.

HETEROCYCLIC DERIVATIVES

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Page/Page column 8, (2009/05/28)

The present invention relates to a heterocyclic derivative according to formula I wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutica

PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS

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Page/Page column 53, (2008/06/13)

The present invention relates to a heterocyclic derivative according to Formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceuti

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