100108-77-8 Usage
Description
L-ALANINE (U-13C3) is an isotope-labeled analog of L-Alanine, a non-essential amino acid that plays a crucial role in human development and is one of the 20 amino acids encoded by the genetic code. L-ALANINE (U-13C3) is specifically designed for in-vivo measurement of glucose and alanine metabolism, particularly in studies involving patients with diabetes.
Uses
Used in Medical Research:
L-ALANINE (U-13C3) is used as a research tool for monitoring glucose and alanine metabolism in patients with diabetes. The isotope labeling allows for a more accurate and detailed analysis of metabolic processes, which can help in understanding the underlying mechanisms of diabetes and potentially lead to the development of more effective treatments.
Used in Pharmaceutical Development:
L-ALANINE (U-13C3) can be utilized in the development of pharmaceuticals targeting diabetes management. By studying the effects of this compound on glucose and alanine metabolism, researchers can gain insights into the potential therapeutic benefits of similar compounds, ultimately contributing to the creation of new drugs for diabetes treatment.
Used in Nutritional Studies:
As a non-essential amino acid, L-ALANINE (U-13C3) can also be employed in nutritional studies to investigate the role of L-Alanine in overall health and well-being. This can provide valuable information on the optimal dietary intake of L-Alanine and its potential impact on various health conditions, including diabetes.
Check Digit Verification of cas no
The CAS Registry Mumber 100108-77-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,1,0 and 8 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 100108-77:
(8*1)+(7*0)+(6*0)+(5*1)+(4*0)+(3*8)+(2*7)+(1*7)=58
58 % 10 = 8
So 100108-77-8 is a valid CAS Registry Number.
100108-77-8Relevant articles and documents
The CFTA method: A reliable procedure for the determination of the absolute configuration of chiral primary amines by 1H NMR spectroscopic analysis
Takeuchi, Yoshio,Segawa, Masaru,Fujisawa, Hidehito,Omata, Kenji,Lodwig, Siegfried N.,Unkefer, Clifford J.
, p. 4617 - 4619 (2006)
Surprisingly stable anti-periplanar conformers of CFTA amides form the basis of a new and very reliable method for determining the absolute configuration of chiral primary amines by 1H NMR spectroscopy (see picture). CFTA = α-cyano-α-fluoro-p-tolylacetic acid. (Chemical Equation Presented).
Stereoselective synthesis of triply isotope-labeled Ser, Cys, and Ala: Amino acids for stereoarray isotope labeling technology
Terauchi, Tsutomu,Kobayashi, Kuniko,Okuma, Kosuke,Oba, Makoto,Nishiyama, Kozaburo,Kainosho, Masatsune
supporting information; experimental part, p. 2785 - 2787 (2009/05/30)
(Chemical Equation Presented) Efficient access to highly enantioselective isotope-labeled serine, cysteine, and alanine for stereoarray isotope labeling (SAIL) is described.
