100117-48-4

Basic information

• Product Name: Benzenebutanoic acid, 4-acetyl-
• CAS NO: 100117-48-4
• Molecular Formula: C12H14O3
• Molecular Weight: 206.241
• Mol File: 100117-48-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenebutanoic acid, 4-acetyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoic acid, 4-acetyl-(100117-48-4)
• EPA Substance Registry System: Benzenebutanoic acid, 4-acetyl-(100117-48-4)

Safety Data

• Hazardous Substances Data: 100117-48-4(Hazardous Substances Data)

Upstream product

• 62926-84-5 1-(4-allylphenyl)ethanone 
• 71665-59-3 4-(4-acetylphenyl)butyric acid ethyl ester 
• 1821-12-1 4-Phenylbutyric acid 
• 10031-93-3 ethyl 4-phenylbutyrate 

Downstream Products

• 100117-94-0 4-<4-(carboxymethyl)phenyl>butyric acid 
• 106949-28-4 7-acetyl-3,4-dihydro-2H-naphthalen-1-one 
• 34162-06-6 4-(3-carboxypropyl)benzoic acid 
• 89781-52-2 8-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid 

Relevant articles and documents

Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals

In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.

Enediyne derivatives useful for the synthesis of conjugates of methyltrithio antitumor agents

This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.