1001334-22-0

Basic information

• Product Name: Benzaldehyde, 5-chloro-2-iodo-
• CAS NO: 1001334-22-0
• Molecular Formula: C7H4ClIO
• Molecular Weight: 266.466
• Mol File: 1001334-22-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 5-chloro-2-iodo-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 5-chloro-2-iodo-(1001334-22-0)
• EPA Substance Registry System: Benzaldehyde, 5-chloro-2-iodo-(1001334-22-0)

Safety Data

• Hazardous Substances Data: 1001334-22-0(Hazardous Substances Data)

Upstream product

• 635-21-2 5-chloroanthranilic acid 
• 13421-00-6 5-chloro-2-iodo-benzoic acid 
• 82386-90-1 5-chloro-2-iodobenzyl alcohol 

Downstream Products

• 1588972-68-2 1-(5-chloro-2-((4-methoxyphenyl)ethynyl)phenyl)-4-hydroxy-4-methylpent-2-yn-1-one 
• 1588973-18-5 C₂₁H₁₉ClO₃ 
• 1588972-33-1 4,7'-dichloro-3,4'-diiodo-3'-(4-methoxyphenyl)-5,5-dimethyl-5H-spiro[furan-2,1'-isochromene] 
• 1588971-97-4 7'-chloro-3,4,4'-triiodo-3'-(4-methoxyphenyl)-5,5-dimethyl-5H-spiro[furan-2,1'-isochromene] 
• 4792-67-0 5-chloro-indole-2-carboxylic acid ethyl ester 

Relevant articles and documents

Palladium-Catalyzed, Norbornene-Mediated, ortho-Amination ipso-Amidation: Sequential C-N Bond Formation

A palladium-catalyzed, norbornene-mediated ortho- and ipso-C-N bond-forming Catellani reaction is reported. This reaction proceeds through a sequential intermolecular amination followed by intramolecular cyclization of a tethered amide. The products, ortho-aminated dihydroquinolinones, were generated in moderate to good yields and are present in bioactive molecules. This work highlights the challenge of competing intra- vs intermolecular palladium-catalyzed processes.

Lewis Acid Catalyzed Formal Intramolecular [3 + 3] Cross-Cycloaddition of Cyclopropane 1,1-Diesters for Construction of Benzobicyclo[2.2.2]octane Skeletons

A novel Lewis acid catalyzed formal intramolecular [3 + 3] cross-cycloaddition (IMCC) of cyclopropane 1,1-diesters has been successfully developed. This supplies an efficient and conceptually new strategy for construction of bridged bicyclo[2.2.2]octane skeletons. This [3 + 3]IMCC could be run up to gram scale and from easily prepared starting materials. This [3 + 3]IMCC, together with our previously reported [3 + 2]IMCC strategy, can afford either the bicyclo[2.2.2]octane or bicyclo[3.2.1]octane skeletons from the similar starting materials by regulating the substituents on vinyl group.

SPIROINDOLINONE DERIVATIVES

There are provided compounds of the formula and pharmaceutically acceptable salts and esters thereof wherein W, V, X, Y, A, R and R' are as described herein. The compounds are useful as anticancer agents.