1001345-89-6

Basic information

• Product Name: 4-amino-3-chloro-N-(1-methyl-4-piperidyl)benzamide
• Synonyms: 4-amino-3-chloro-N-(1-methyl-4-piperidyl)benzamide
• CAS NO: 1001345-89-6
• Molecular Weight: 267.758
• Mol File: 1001345-89-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-amino-3-chloro-N-(1-methyl-4-piperidyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-3-chloro-N-(1-methyl-4-piperidyl)benzamide(1001345-89-6)
• EPA Substance Registry System: 4-amino-3-chloro-N-(1-methyl-4-piperidyl)benzamide(1001345-89-6)

Safety Data

• Hazardous Substances Data: 1001345-89-6(Hazardous Substances Data)

Upstream product

• 55737-29-6 3-chloro-4-nitro-benzoic acid chloride 
• 39608-47-4 3-chloro-4-nitrobenzoic acid 
• 41838-46-4 4-Amino-1-methylpiperidine 
• 2486-71-7 4-amino-3-chlorobenzoic acid 
• 1001345-90-9 3-chloro-N-(1-methyl-4-piperidyl)-4-nitro-benzamide 

Downstream Products

• 1137867-59-4 3-chloro-4-(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-N-(1-methyl-piperidin-4-yl)-benzamide 
• 1018317-90-2 3-chloro-4-[(7-cyclopentyI-8-ethyI-10-methyl-9-oxo-3,5,7,8,10-pentazabicycIo[4.4.0]deca-1,3,5-trien-4-yl)amino]-N-(1-methyI-4-piperidyl)benzamide 

Relevant articles and documents

(5,6-DIHYDRO)PYRIMIDO[4,5-E]INDOLIZINES

The invention relates to a compound of Formula (I) wherein, R1 and R2 independently are selected from the group consisting of optionally substituted (6-10C)aryl and (1-5C)heteroaryl groups. The compounds can be used in pharmaceutical compositions, in particular in the treatment of cancer.

HALO-SUBSTITUTED PYRIMIDODIAZEPINES

The present invention provides PLK1 inhibitor compounds of formula I: useful in the treatment or control of cell proliferative disorders, particularly oncological disorders. These compounds and formulations containing such compounds may be useful in the treatment or control of solid tumors, such as, for example, breast, colon, lung and prostate tumors and other oncological diseases such as non-Hodgkin's lymphomas. Also provided are intermediate compounds useful in the synthesis of compounds of formula I.

NOVEL COMPOUNDS

There is provided a compound of formula (I): processes for the manufacture thereof, pharmaceutical compositions thereof and uses in therapy.