1001397-69-8 Usage
General Description
The chemical "1,1-dimethylethyl 4-(1H-indol-4-yloxy)-1-piperidinecarboxylate" is a compound consisting of a piperidine ring attached to an indole group through an ether linkage. It is also known as "Tadalafil," which is a medication used to treat erectile dysfunction and benign prostatic hyperplasia. Tadalafil works by inhibiting the enzyme phosphodiesterase type 5, leading to increased blood flow to the penis during sexual stimulation. This results in improved erectile function. Tadalafil is a prescription drug and should be used under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 1001397-69-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,1,3,9 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1001397-69:
(9*1)+(8*0)+(7*0)+(6*1)+(5*3)+(4*9)+(3*7)+(2*6)+(1*9)=108
108 % 10 = 8
So 1001397-69-8 is a valid CAS Registry Number.
1001397-69-8Relevant articles and documents
Discovery of 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines as orally available g protein-coupled receptor 119 agonists
Katamreddy, Subba R.,Carpenter, Andrew J.,Ammala, Carina E.,Boros, Eric E.,Brashear, Ron L.,Briscoe, Celia P.,Bullard, Sarah R.,Caldwell, Richard D.,Conlee, Christopher R.,Croom, Dallas K.,Hart, Shane M.,Heyer, Dennis O.,Johnson, Paul R.,Kashatus, Jennifer A.,Minick, Doug J.,Peckham, Gregory E.,Ross, Sean A.,Roller, Shane G.,Samano, Vicente A.,Sauls, Howard R.,Tadepalli, Sarva M.,Thompson, James B.,Xu, Yun,Way, James M.
, p. 10972 - 10994 (2013/02/25)
GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor 119
