1001414-89-6

Basic information

• Product Name: tert-butyl (R)-(1-cyclopropyl-2-hydroxyethyl)carbamate
• CAS NO: 1001414-89-6
• Molecular Weight: 201.266
• Mol File: 1001414-89-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: tert-butyl (R)-(1-cyclopropyl-2-hydroxyethyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (R)-(1-cyclopropyl-2-hydroxyethyl)carbamate(1001414-89-6)
• EPA Substance Registry System: tert-butyl (R)-(1-cyclopropyl-2-hydroxyethyl)carbamate(1001414-89-6)

Safety Data

• Hazardous Substances Data: 1001414-89-6(Hazardous Substances Data)

Usage

General Description

Tert-butyl (R)-(1-cyclopropyl-2-hydroxyethyl)carbamate is a chemical compound primarily used as a protective agent in the synthesis of pharmaceuticals, specifically in the protection of hydroxyl groups. It is a derivative of carbamic acid and contains a cyclopropyl ring attached to a hydroxyethyl group, with a tert-butyl moiety providing steric hindrance and stability. tert-butyl (R)-(1-cyclopropyl-2-hydroxyethyl)carbamate is commonly employed in organic chemistry reactions to prevent unwanted side reactions or to control the stereochemistry of a molecule. Tert-butyl (R)-(1-cyclopropyl-2-hydroxyethyl)carbamate is a valuable tool for chemists and researchers in the field of medicinal chemistry and drug development.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1270290-36-2 (R)-2-amino-2-cyclopropylethan-1-ol 
• 49607-01-4 (R)-2-amino-2-cyclopropylacetic acid 
• 54256-41-6 N-(R)-2-(tertbutoxycarbonylamino)-2-cyclopropylacetic acid 
• 936097-43-7 methyl (S)-2-(N-tert-butoxycarbonylamino)-2-cyclopropylacetate 

Downstream Products

• 1428768-78-8 C₁₈H₂₁ClFN₃O₂ 
• 1428768-79-9 C₁₉H₂₄FN₃O₂ 
• 1428768-60-8 C₁₄H₁₈N₂O 
• 1428768-63-1 C₁₆H₁₆Cl₂N₂O₂ 
• 1428768-62-0 C₁₆H₁₆Br₂N₂O₂ 
• 1428768-65-3 C₂₅H₂₈ClN₃O₃ 
• 1428768-69-7 C₂₅H₂₈BrN₃O₃ 
• 1428768-70-0 C₂₄H₂₇BrN₄O₃ 
• 1428768-66-4 C₂₆H₃₁N₃O₃ 
• 1428768-67-5 C₂₅H₃₀N₄O₃ 
• 1428768-74-4 C₁₉H₂₄ClN₃O₅S 
• 1428768-75-5 C₂₀H₂₇N₃O₅S 
• 1428768-58-4 C₁₂H₁₇NO 
• 1173523-52-8 (R)-5-chloro-1-(1-cyclopropyl-2-hydroxyethyl)-3-(4-methoxy-2,5-dimethylphenylamino)pyrazin-2(1H)-one 

Relevant articles and documents

Synthesis of Chiral Tryptamines via a Regioselective Indole Alkylation

A practical synthesis of chiral tryptamines from simple, unprotected indoles has been developed. Indole nucleophiles prepared with MeMgCl in the presence of CuCl reacted with chiral cyclic sulfamidates almost exclusively at the C3-position of i

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Potential CRF1R PET imaging agents: 1-Fluoroalkylsubstituted 5-halo-3-(arylamino)pyrazin-2(1H)-ones

A series of pyrazinones were prepared and evaluated as potential CRF 1R PET imaging agents. Optimization of their CRF1R binding potencies and octanol-phosphate buffer phase distribution coefficients are discussed herein.