100142-91-4

Basic information

• Product Name: 3-methyl-2-thioxo-2,3-dihydro-imidazole-1-carboxylic acid benzyl ester
• CAS NO: 100142-91-4
• Molecular Weight: 248.305
• Mol File: 100142-91-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methyl-2-thioxo-2,3-dihydro-imidazole-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-2-thioxo-2,3-dihydro-imidazole-1-carboxylic acid benzyl ester(100142-91-4)
• EPA Substance Registry System: 3-methyl-2-thioxo-2,3-dihydro-imidazole-1-carboxylic acid benzyl ester(100142-91-4)

Safety Data

• Hazardous Substances Data: 100142-91-4(Hazardous Substances Data)

Upstream product

• 60-56-0 1-methyl-1,3-dihydro-imidazole-2-thione 
• 501-53-1 benzyl chloroformate 
• 616-47-7 1-methyl-1H-imidazole 

Relevant articles and documents

Antithyroid drug carbimazole and its analogues: Synthesis and inhibition of peroxidase-catalyzed iodination of L-tyrosine

Synthesis and biological activity of the antithyroid drug carbimazole (CBZ) and its analogues are described. The introduction of an ethoxycarbonyl group in methimazole and its selenium analogue not only prevents the oxidation to the corresponding disulfide and diselenide but also reduces the zwitterionic character. A structure-activity correlation in a series of CBZ analogues suggests that the presence of a methyl substituent in CBZ and related compounds is important for their antithyroid activity.