100156-48-7

Basic information

• Product Name: 1-O-octadecyl-2-O-methylglycerol
• Synonyms: 1-O-octadecyl-2-O-methylglycerol
• CAS NO: 100156-48-7
• Molecular Formula: C22H44O4
• Molecular Weight: 0
• Mol File: 100156-48-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 461.9°Cat760mmHg
• Flash Point: 142.6°C
• Appearance: /
• Density: 0.932g/cm³
• Vapor Pressure: 1.8E-10mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: 1-O-octadecyl-2-O-methylglycerol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-octadecyl-2-O-methylglycerol(100156-48-7)
• EPA Substance Registry System: 1-O-octadecyl-2-O-methylglycerol(100156-48-7)

Safety Data

• Hazardous Substances Data: 100156-48-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H44O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(24)26-20-21(19-23)25-2/h21,23H,3-20H2,1-2H3

Upstream product

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• 761-06-8 2-methylglycerol 
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Relevant articles and documents

The chemical synthesis and cytotoxicity of new sulfur analogues of 2-methoxy-lysophosphatidylcholine

The chemical synthesis of phosphorothioate/phosphorodithioate analogues of 2-methoxy-lysophosphatidylcholine has been described. For the preparation of new sulfur derivatives of lysophosphatidylcholine both oxathiaphospholane and dithiaphospholane approaches have been employed. Each lysophospholipid analogue was synthesized as a series of five compounds, bearing different fatty acid residues both saturated (12:0, 14:0, 16:0, 18:0) and unsaturated (18:1). The methylation of glycerol 2-hydroxyl function was applied in order to increase the stability of prepared analogues by preventing 1→2 acyl migration. The cellular toxicity of newly synthesized 2-methoxy-lysophosphatidylcholine derivatives was measured using MTT viability assay and lactate dehydrogenase release method.

The chemical synthesis and preliminary biological studies of phosphodiester and phosphorothioate analogues of 2-methoxy-lysophosphatidylethanolamine

The chemical synthesis of phosphorothioate/phosphodiester analogues of 2-methoxy-lysophosphatidylethanolamine has been described. For the preparation of phosphorothioate derivatives oxathiaphospholane approach has been employed. The phosphodiester compounds were prepared by OXONE oxidation of corresponding phosphorothioates. Each lysophospholipid analogue was synthesized as a series of four compounds, bearing different fatty acid residues both saturated (14:0, 16:0, 18:0) and unsaturated (18:1). The methylation of glycerol 2-hydroxyl function was applied in order to increase the stability of prepared analogues by preventing 1→2 acyl migration. The cytotoxicity of newly synthesized 2-methoxy-lysophosphatidylethanolamine derivatives was evaluated with resazurin-based method in prostate cancer PC3 cell line. The highest reduction of cell viability was noted for LPE analogues containing myristoyl acyl chain.

Hair growers

The present invention provides a hair growth promoting composition having an excellent hair growth promoting effect. The hair promoting composition comprises, as an effective ingredient, a composition expressed by following Formula (I): wherein one of R1 to R4 is selected from a group of C14-22 alkyl, C14-22 alkoxy and C14-22 acyloxy groups, and the others are selected from a group of H, OH, C1-3 alkyl and C1-3 alkoxy groups; and when R1 is C14-22 alkoxy group and one of R2 and R4 is C1-3 alkoxy group, R3 is H, C1-3 alkyl or C1-3 alkoxy group; and when R1 is C14-22 acyloxy group, at least one of R2 to R4 is C1-3 alkoxy group.