100157-36-6

Basic information

• Product Name: 3-(3,4-dimethoxy-phenyl)-propionaldehyde-oxime
• Synonyms: 3-(3,4-dimethoxy-phenyl)-propionaldehyde-oxime
• CAS NO: 100157-36-6
• Molecular Weight: 209.245
• Mol File: 100157-36-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(3,4-dimethoxy-phenyl)-propionaldehyde-oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-dimethoxy-phenyl)-propionaldehyde-oxime(100157-36-6)
• EPA Substance Registry System: 3-(3,4-dimethoxy-phenyl)-propionaldehyde-oxime(100157-36-6)

Safety Data

• Hazardous Substances Data: 100157-36-6(Hazardous Substances Data)

Upstream product

• 61871-67-8 3-(3,4-Dimethoxyphenyl)propanal 
• 3929-47-3 3-(3,4-dimethoxyphenyl)-1-propanol 
• 5462-13-5 ethyl 3-(3,4-dimethoxyphenyl)propionate 
• 20583-78-2 3,4-dimethoxy-cinnamic acid ethyl ester 
• 2316-26-9 3,4-dimethoxycinnamic acid 
• 100157-46-8 3-(3,4-dimethoxyphenyl)-1,1-ethylendioxy-2-propene 
• 100157-47-9 3-(3,4-dimethoxyphenyl)-1,1-ethylendioxypropane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Relevant articles and documents

In silico design and synthesis of N-arylalkanyl 2-naphthamides as a new class of non-purine xanthine oxidase inhibitors

A series of N-arylalkanyl 2-naphthamides (Xa~e), which were predicted from virtual molecular docking on a built xanthine oxidase template as potential inhibitors, were synthesized. Their inhibitory activity against xanthine oxidase was assayed. Among these prepared, compounds Xb (IC50 13.6?μM), Xc (IC50 13.1?μM), and Xd (IC50 12.5?μM) showed comparable inhibitory activity to allopurinol (IC50 22.1?μM). The in vitro assay result correlated well with molecular docking scores, ΔG?=??16.99, ?17.66, and ?17.13 Kcal/mol, respectively. On the potassium oxonate-induced hyperuricemic mice model, oral administration of Xc-Ac (40 mg/ Kg), the per-O-acetylated Xc, could reduce the blood uric acid level by 60% in comparison to the normal control group and is statistically significant (p .01) while compared with the hyperuricemic mice group.