10017-66-0 Usage
General Description
Pseudouridine is a naturally occurring isomer that is found in various substances, including wheat bran. It is considered a modified nucleoside that is present in different types of RNA, and contributes to the structure and function of RNA molecules. Pseudouridine contributes in stability, activity, and post-transcriptional modifications of RNA. Its presence in wheat bran is due to its ubiquity in the plant kingdom and its role in RNA. It is also used as a biomarker for diseases and in research on the microbiome, in addition to playing a role in biotechnology and pharmacology. It is not directly associated with any harmful effects and is generally seen as a positive element in nutrition and functionality. Some studies show it may have potential health benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 10017-66-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,0,1 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 10017-66:
(7*1)+(6*0)+(5*0)+(4*1)+(3*7)+(2*6)+(1*6)=50
50 % 10 = 0
So 10017-66-0 is a valid CAS Registry Number.
10017-66-0Relevant articles and documents
A Synthesis of Pseudouridine
Brown, Daniel M.,Ogden, Richard C.
, p. 723 - 725 (2007/10/02)
2,3,5-Tri-O-benzylribose and 2,4-di-t-butoxy-5-lithiopyrimidine (from the 5-bromo-compound and butyllithium) in THF at -78 deg C give 5-(2,3,5-tri-O-benzyl-D-altro-pentahydroxypentyl)-2,4-di-t-butoxypyrimidine and its D-allo-epimer (ratio 5:2), which cyclise sterospecifically in ethanolic hydrochloric acid to 5-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)uracil and its α-anomer.Debenzylation by boron trichloride gives 5-β-D-ribofuranosyluracil, pseudouridine, and its α-anomer. 2,3,5-Tri-O-methylribose reacts analogously. 2,3-O-Isopropylideneribose and its 5-O-trityl derivative give no polyol, but instead 2,4-di-t-butoxy-5-(2-hydroxyisopropyl)pyrimidine.
