100191-87-5

Basic information

• Product Name: 4-(Allyloxy)-3,5-dimethylbenzonitrile
• Synonyms: 4-(Allyloxy)-3,5-dimethylbenzonitrile
• CAS NO: 100191-87-5
• Molecular Formula: C₁₂H₁₃NO
• Molecular Weight: 187.23772
• Mol File: 100191-87-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 325.3°Cat760mmHg
• Flash Point: 137.3°C
• Appearance: /
• Density: 1.02g/cm³
• Vapor Pressure: 0.000232mmHg at 25°C
• Refractive Index: 1.524
• CAS DataBase Reference: 4-(Allyloxy)-3,5-dimethylbenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Allyloxy)-3,5-dimethylbenzonitrile(100191-87-5)
• EPA Substance Registry System: 4-(Allyloxy)-3,5-dimethylbenzonitrile(100191-87-5)

Safety Data

• Hazardous Substances Data: 100191-87-5(Hazardous Substances Data)

Usage

General Description

4-(Allyloxy)-3,5-dimethylbenzonitrile is a chemical compound with the molecular formula C13H13NO. It is a nitrile compound, featuring a benzene ring with two methyl groups at the 3 and 5 positions, as well as an allyloxy group at the 4 position. 4-(Allyloxy)-3,5-dimethylbenzonitrile is commonly used in organic synthesis and chemical research as a building block for more complex molecules. Its unique structure and reactivity make it a valuable intermediate for the production of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, 4-(Allyloxy)-3,5-dimethylbenzonitrile may have potential applications in the development of new materials and chemical processes due to its versatile chemical properties.

InChI:InChI=1/C12H13NO/c1-4-5-14-12-9(2)6-11(8-13)7-10(12)3/h4,6-7H,1,5H2,2-3H3

Upstream product

• 7192-39-4 4-(allyloxy)-3,5-dimethylbenzoic acid 
• 4198-90-7 3,5-dimethyl-4-hydroxybenzonitrile 
• 106-95-6 allyl bromide 
• 4919-37-3 3,5-dimethyl-4-hydroxybenzoic acid 
• 7192-65-6 4-Allyloxy-3,5-dimethyl-benzoesaeure-amid 
• 576-26-1 2.6-dimethylphenol 

Downstream Products

• 1010113-34-4 4-allyloxy-N-hydroxy-3,5-dimethyl-benzamidine 
• 1311285-34-3 (4-{5-[butyl(2-fluorobenzyl)amino]-1,3,4-thiadiazol-2-yl}-2,6-dienethylphenoxy)acetaldehyde 
• 1311285-33-2 5-[4-(allyloxy)-3,5-dimethylphenyl]-N-butyl-N-(2-fluorobenzyl)-1,3,4-thiadiazol-2-amine 
• 1314862-85-5 C₂₄H₂₆ClN₃O₂S 
• 1282613-40-4 tert-butyl 1-(2-(4-(5-(butylamino)-1,3,4-thiadiazol-2-yl)-2,6-dimethylphenoxy)ethyl)piperidine-4-carboxylate 
• 1282614-58-7 N-butyl-2-fluoro-N-[5-(4-{2-[(2-hydroxyethyl)(methyl)amino]ethoxy}-3,5-dimethylphenyl)-1,3,4-thiadiazol-2-yl]benzamide 
• 1282613-31-3 1-[2-(4-{5-[Butylamino]-1,3,4-thiadiazol-2-yl}-2,6-dimethylphenoxy)ethyl]piperidin-4-carboxylic acid 
• 1282613-30-2 2-(4-(5-(butylamino)-1,3,4-thiadiazol-2-yl)-2,6-dimethylphenoxy)acetaldehyde 
• 1282613-26-6 N-butyl-3-chloro-N-(5-(3,5-dimethyl-4-(2-oxoethoxy)phenyl)-1,3,4-thiadiazol-2-yl)-2-fluorobenzamide 
• 1282613-25-5 N-butyl-2-chloro-N-(5-(3,5-dimethyl-4-(2-oxoethoxy)phenyl)-1,3,4-thiadiazol-2-yl)benzamide 
• 1282613-24-4 N-(5-(4-(allyloxy)phenyl)-1,3,4-thiadiazol-2-yl)-N-butyl-2-chlorobenzamide 
• 1282613-23-3 N-butyl-N-(5-(3,5-dimethyl-4-(2-oxoethoxy)phenyl)-1,3,4-thiadiazol-2-yl)-2-methylbenzamide 
• 1282613-00-6 N-butyl-N-(5-(3,5-dimethyl-4-(2-oxoethoxy)phenyl)-1,3,4-thiadiazol-2-yl)-2-fluorobenzamide 
• 1282612-99-0 N-(5-(4-(Allyloxy)-3,5-dimethylphenyl)-1,3,4-thiadiazol-2-yl)-N-butyl-2-fluorobenzamide 

Relevant articles and documents

NEW 2-AMINOTHIADIAZOLE DERIVATIVES

The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or N-oxide thereof: wherein:. L represents a direct bond or a -S(O)2- group, ? n is an integer having a value from 0 to 2, ? R1 represents a pyridyl group or an imidazo[1,2-α]pyridinyl group, wherein the pyridyl group is substituted with one or more substituents selected from halogen atoms, a hydroxy group, a C1-4 alkyl group and a C1-4 alkoxy group, or ? R1 represents a group of formula: wherein:. Ra and Rb independently represent a hydrogen atom, halogen atom or a linear or branched C1-4, alkyl group,. Rc represents a hydroxy group, a linear or branched C1-4 alkyl group or C1-4 alkoxy group wherein the alkyl and the alkoxy groups independently are optionally substituted with one or more substituents selected from hydroxy group, cyano group and-NR'R" groups and wherein R' represents a hydrogen atom or a linear or branched C1-4 alkyl group, R" represents a hydrogen atom or a linear or branched C1-4 alkyl group optionally substituted with a hydroxycarbonyl group; or R' and R" together with the nitrogen atom to which they are attached form a 4 to 6 membered, saturated heterocyclic ring optionally substituted with a hydroxycarbonyl group.. R2 represents a pyridyl group, a C3-6 cycloalkyl group or a phenyl group which is optionally substituted with one or more substituents selected from halogen atoms, cyano group, and C1-4 alkoxy group; and. R3 represents a C3-6 cycloalkyl group, a C3-6 cycloalkyl-C1-2 alkyl group or a linear or branched C2-4 alkyl group optionally substituted with one or more substituents selected from halogen atoms and C1-2 alkoxy group.

NEW THIADIAZOLE DERIVATIVES

The present invention relates to thiadiazole derivatives of formula (I), to processes for their preparation and to pharmaceutical compositions containing them. These compounds are potent agonists of S1P1 receptors and thus, they are useful In the treatment, prevention or suppression of diseases and disorders known to be susceptible to improvement by sphingosine-1-phosphate receptors agonists (S1P1), such as autoimmune diseases, chronic immune and inflammatory diseases, transplant rejection, malignant neoplastic diseases, angiogenic-related disorders, pain, neurological diseases, viral and infectious diseases.

NEW 2-AMIDOTHIADIAZOLE DERIVATIVES

New 2-amidothiadiazole derivatives having the chemical structure of formula (I) or pharmaceutically acceptable salts or N-oxides thereof as agonists of S1P1 receptors.