10022-81-8

Basic information

• Product Name: methyl 1-methyl-3,4-dihydro-2H-beta-carboline-3-carboxylate
• CAS NO: 10022-81-8
• Molecular Formula: C₁₄H₁₄N₂O₂
• Molecular Weight: 242.2732
• Mol File: 10022-81-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 437.9°C at 760 mmHg
• Flash Point: 218.6°C
• Density: 1.31g/cm³
• Vapor Pressure: 7.22E-08mmHg at 25°C
• Refractive Index: 1.653
• CAS DataBase Reference: methyl 1-methyl-3,4-dihydro-2H-beta-carboline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-methyl-3,4-dihydro-2H-beta-carboline-3-carboxylate(10022-81-8)
• EPA Substance Registry System: methyl 1-methyl-3,4-dihydro-2H-beta-carboline-3-carboxylate(10022-81-8)

Safety Data

• Hazardous Substances Data: 10022-81-8(Hazardous Substances Data)

Upstream product

• 2824-57-9 N-acetyl-L-tryptophan methyl ester 
• 4299-70-1 L-tryptophan methyl ester 
• 81801-79-8 N^α-methylthiocarbonyltryptophan methyl ester 
• 2824-57-9 N-acetyltryptophan methyl ester 
• 5619-09-0 methyl tryptophanate hydrochloride 
• 67-56-1 methanol 
• 10022-82-9 D,L-1-Methyl-3,4-dihydro-β-carboline-3-carboxylic acid 

Downstream Products

• 16641-82-0 1-methyl-β-carboline-3-carboxylic acid methyl ester 

Relevant articles and documents

Aromatization and chemoselective alkylation of 1-methyl-3,4-dihydro-β-carboline-3-carboxylic acid and its derivatives

Unprecedented aromatization was observed during N-alkylation reactions of 1-methyl-3,4-dihydro-β-carboline-3-carboxylic acid methyl ester, giving rise to 9-alkyl-1-methyl-β-carboline-3-carboxylic acid methyl esters. Inverse addition of base during a simil

Synthesis and evaluation of β-carboline derivatives as inhibitors of human immunodeficiency virus

A series of β-carboline derivatives were synthesized by utilizing aromatization and chemoselective alkylation method recently reported from our laboratory. Synthesized derivatives were evaluated for anti-HIV activity in human CD4+ T cell line (CEM-GFP) infected with HIV-1 NL4.3 virus. 1-Formyl-β-carboline-3-carbxylic acid methyl ester (15) showed inhibition of human immunodeficiency virus at IC50 = 2.9 μM.