1002404-84-3

Basic information

• Product Name: 2-benzylhexahydroimidazo[1,5-a]pyrazin-3(2H)-one
• Synonyms: 2-benzylhexahydroimidazo[1,5-a]pyrazin-3(2H)-one
• CAS NO: 1002404-84-3
• Molecular Weight: 231.297
• Mol File: 1002404-84-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzylhexahydroimidazo[1,5-a]pyrazin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzylhexahydroimidazo[1,5-a]pyrazin-3(2H)-one(1002404-84-3)
• EPA Substance Registry System: 2-benzylhexahydroimidazo[1,5-a]pyrazin-3(2H)-one(1002404-84-3)

Safety Data

• Hazardous Substances Data: 1002404-84-3(Hazardous Substances Data)

Upstream product

• 143540-05-0 2-hydroxymethylpiperazine-1,4-dicarboxylic acid di-tert-butyl ester 
• 1256815-88-9 tert-butyl 2-benzylhexahydro-3-oxoimidazo[1,5-a]pyrazine-7(1H)-carboxylate 
• 1246551-25-6 tert-butyl 3-oxo-1,2,5,6,8,8a-hexahydroimidazo[1,5-a]pyrazine-7-carboxylate 
• 1256815-07-2 di-tert-butyl 2-(aminomethyl)piperazine-1,4-dicarboxylate 
• 1256815-06-1 di-tert-butyl 2-((1,3-dioxoisoindolin-2-yl)methyl)-piperazine-1,4-dicarboxylate 

Downstream Products

• 1256815-27-6 (3R)-3-(benzyloxyamino)-1-[2-benzyl-hexahydro-3-oxoimidazo[1,5-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one 

Relevant articles and documents

Convenient synthesis of novel 2-substituted imidazopyrazinone derivatives

Starting from commercially available piperazine-2-carboxylic acid, a series of novel 2-aryl and 2-benzyl substituted imidazopyrazinone were prepared. The intermediates 5a-g were obtained through facile Buchwald-Hartwig coupling reaction, and the effects of catalyst, base, and solvent on the coupling reaction were investigated. The optimal reaction conditions for the coupling reaction were PdCl2(dppf)=NaO-t-Bu=toluene. Taylor & Francis Group, LLC.