100256-40-4

Basic information

• Product Name: Benzoic acid, 2-butyl-, methyl ester
• Synonyms: Benzoic acid, 2-butyl-, methyl ester
• CAS NO: 100256-40-4
• Molecular Weight: 192.258
• Mol File: 100256-40-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-butyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-butyl-, methyl ester(100256-40-4)
• EPA Substance Registry System: Benzoic acid, 2-butyl-, methyl ester(100256-40-4)

Safety Data

• Hazardous Substances Data: 100256-40-4(Hazardous Substances Data)

Upstream product

• 6638-68-2 4,5-dimethyl-2-phenyl-1,3,2-dioxaborolane 
• 95667-98-4 methyl 2-((methylsulfonyl)oxy)benzoate 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 1461-25-2 tetra-n-butyltin(IV) 
• 1409942-08-0 methyl 2-(but-1-yn-1-yl)benzoate 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 701923-86-6 3-Chloro-N-(2-hydroxy-1,1-dimethyl-ethyl)-benzamide 
• 80762-49-8 2-(m-chlorophenyl)-4,4-dimethyl-4,5-dihydrooxazole 
• 618-46-2 m-Chlorobenzoyl chloride 
• 57629-47-7 2-(2-Butylphenyl)-4,4-dimethyl-2-oxazoline 
• 118-90-1 ortho-methylbenzoic acid 
• 109-72-8 n-butyllithium 
• 477338-82-2 2-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-4,5-dimethyl-[1,3,2]dioxaborolane 
• 67-56-1 methanol 

Downstream Products

• 66810-79-5 (2-butylphenyl)methanol 
• 54887-23-9 2-butylbenzoic acid 

Relevant articles and documents

Nickel-catalyzed coupling reaction of lithium organoborates and aryl mesylates possessing an electron withdrawing group

In the presence of NiCl2(PPh3)2 as catalyst, p-methoxycarbonylphenyl mesylate (5) and tosylate (6) react with lithium arylborates 4 (Ar = 2-furyl, Ph, p-Me-Ph, p-MeO-Ph) at room temperature to afford the coupling products in high yields. Similarly, mesylates 9-11 coupled with these borates 4 efficiently.

Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response

Quorum sensing is a mechanism of chemical communication among bacteria that enables collective behaviors. In V. cholerae, the etiological agent of the disease cholera, quorum sensing controls group behaviors including virulence factor production and biofilm formation. The major V. cholerae quorum-sensing system consists of the extracellular signal molecule called CAI-1 and its cognate membrane bound receptor called CqsS. Here, the ligand binding activity of CqsS is probed with structural analogues of the natural signal. Enabled by our discovery of a structurally simplified analogue of CAI-1, we prepared and analyzed a focused library. The molecules were designed to probe the effects of conformational and structural changes along the length of the fatty acid tail of CAI-1. Our results, combined with pharmacophore modeling, suggest a molecular basis for signal molecule recognition and receptor fidelity with respect to the fatty acid tail portion of CAI-1. These efforts provide novel probes to enhance discovery of antivirulence agents for the treatment of V. cholerae.

The effect of diethylamine on Stille alkylations with tetraalkylstannanes

The addition of diethylamine to Stille alkylation reactions using stannanes improves yields by reducing β-hydride elimination and reduction reactions, it also serves as a substitute for other additives such as Cu(I)I.