100278-39-5

Basic information

• Product Name: 3,4,5-trimethoxy-N-(4-{[(2E)-2-(2-nitrobenzylidene)hydrazinyl]carbonyl}phenyl)benzamide
• CAS NO: 100278-39-5
• Molecular Formula: C₂₄H₂₂N₄O₇
• Molecular Weight: 478.4541
• Mol File: 100278-39-5.mol
• Article Data: 1

Chemical Properties

• Density: 1.315g/cm³
• Refractive Index: 1.607
• CAS DataBase Reference: 3,4,5-trimethoxy-N-(4-{[(2E)-2-(2-nitrobenzylidene)hydrazinyl]carbonyl}phenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5-trimethoxy-N-(4-{[(2E)-2-(2-nitrobenzylidene)hydrazinyl]carbonyl}phenyl)benzamide(100278-39-5)
• EPA Substance Registry System: 3,4,5-trimethoxy-N-(4-{[(2E)-2-(2-nitrobenzylidene)hydrazinyl]carbonyl}phenyl)benzamide(100278-39-5)

Safety Data

• Hazardous Substances Data: 100278-39-5(Hazardous Substances Data)

Upstream product

• 1849-89-4 N-<4-Ethoxycarbonyl-phenyl>-3,4,5-trimethoxy-benzoesaeure-amid 
• 69319-33-1 4-(3,4,5-trimethoxybenzamido)benzoylhydrazide 
• 552-89-6 2-nitro-benzaldehyde 

Relevant articles and documents

Studies on thiazolidin-4-ones: Part XX-synthesis and antimicrobial activity of 2-aryl-5H/methyl/carboxymethyl-3-[4-(3,4,5-trimethoxybenzamido)-benzoylamino] thiazolidin-4-ones

2-Aryl-5-H/methyl/carboxymethyl-3-[4-(3,4,5-trimethoxybenzamido) benzoylamino]thiazolidin-4-ones (3a-m, 4a-m and 5a-m) have been synthesised by the cyclocondensation of thioglycolic acid/thiolactic acid/thiomalic acid with N-substituted benzal-4-(3,4,5-trimethoxybenzamido)benzoylhydrazines (2a-m) which in turn are prepared by the action of aryldehydes on 4-(3,4,5-trimethoxybenzamido)benzoylhydrazide (1). The structures of the compounds 2a-m, 3a-m and 5a-m have been confirmed from elemental analysis, IR, 1H NMR and mass spectral data. All the products are evaluated for their in vitro growth inhibitory activity against several microbes like S. aureus, S. pyogens, E. coli, K. arogens and A. niger.