100281-88-7Relevant articles and documents
BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS
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Page/Page column 20, (2009/03/07)
The present invention relates to compounds of formula (I) wherein R1 and A are as defined in the specification as dual modulators of the serotonin 5-HT2a and dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use as medicaments. Compounds of general formula (I) have high affinity for the dopamine D3 and serotonin (5-Hydroxytryptamine; 5-HT) 5-HT2A receptors and are effective in the treatment of psychotic disorders, as well as other diseases such as depression and anxiety, drug dependence, dementias and memory impairment.
Chiral Sulfoxides in Asymmetric Synthesis: A New Chiral Synthesis of Optically Active 4-Substituted Cyclohexylideneacetic Acid Esters
Solladie, Guy,Zimmermann, Richard,Bartsch, Richard,Walborsky, Harry M.
, p. 662 - 665 (2007/10/02)
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