100298-26-8Relevant articles and documents
Synthesis and R eactions of Some 2,2-Disubstitued 1,2-Diazetidin-3-ones: An Intramolecular Aldol Approach to Bicyclic Systems
Taylor, Edward C.,Davies, Huw M. L.,Hinkle, Jeffery S.
, p. 1530 - 1536 (2007/10/02)
Several procedures have been developed for alkylation at N-2 of a variety of 1,2-diazetidin-3-ones with N-1 substituent carrying an olefinic bond.Ozonolysis yielded aldehydes which were subjected to aldol cyclization conditions.The products proved to be rearranged bicyclic products arising from intramolecular ring opening of the 1,2-diazetidin-3-one lactam bond by the secondary hydroxyl group formed in the aldol reaction.