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10030-78-1

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10030-78-1 Usage

General Description

6-HYDROXY-2-METHYLAMINOPURINE, also known as 6-Methylaminopurine-9-hydroxide, is a purine derivative that is often used in biochemical research as a non-specific protein kinase inhibitor. It is an analog of adenine and acts as a competitive inhibitor of various kinases, including cyclic AMP-dependent protein kinases and protein kinase C. 6-HYDROXY-2-METHYLAMINOPURINE has been found to inhibit the proliferation of leukemia and breast cancer cells, making it a potential candidate for further development as an anti-cancer agent. Additionally, 6-HYDROXY-2-METHYLAMINOPURINE has also been studied for its potential to stimulate plant growth and development, as it can act as a cytokinin, a class of plant hormones that regulate cell division and differentiation.

Check Digit Verification of cas no

The CAS Registry Mumber 10030-78-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,0,3 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10030-78:
(7*1)+(6*0)+(5*0)+(4*3)+(3*0)+(2*7)+(1*8)=41
41 % 10 = 1
So 10030-78-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H7N5O/c1-7-6-10-4-3(5(12)11-6)8-2-9-4/h2-3H,1H3,(H2,7,8,9,10,11,12)

10030-78-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(methylamino)-3,7-dihydropurin-6-one

1.2 Other means of identification

Product number -
Other names N2-Methylguanine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10030-78-1 SDS

10030-78-1Relevant articles and documents

A Convenient Synthesis of N2-Alkylated Guanines

Zhu,Qin,Liu,Luo

, p. 874 - 878 (2019)

An improved three-step synthesis of N2-alkylated guanines has been developed starting from N2-Boc-protected 2-amino-6-chloropurine which was treated with Boc2O, and the resulting doubly N2,9-protected derivative was subjected to N2-alkylation with alkyl halides, followed by hydrolysis. The advantages of this procedure include short reaction steps, simple operations, and good yields.

Synthesis of N2-alkyl(aryl, dialkyl, cycloalkyl)guanines

Kochergin,Persanova,Aleksandrova,Gutorov,Korsunskii

, p. 338 - 341 (2007/10/03)

Novel N2-alkyl(aryl, dialkyl, cycloalkyl)guanines have been synthesized by treating 2-chloro-7-benzylhypoxanthine with amines and debenzylation of the N2-substituted 7-benzylguanine products by means of palladium catalyzed hydrogenat

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