100311-54-4

Basic information

• Product Name: 1-(2-nitrophenyl)ethanamine
• Synonyms: 1-(2-nitrophenyl)ethanamine;1-(2-NITROPHENYL)ETHAN-1-AMINE
• CAS NO: 100311-54-4
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.1772
• Mol File: 100311-54-4.mol

Chemical Properties

• Boiling Point: 301.4±17.0 °C(Predicted)
• Appearance: /
• Density: 1.199±0.06 g/cm3(Predicted)
• PKA: 7.80±0.10(Predicted)
• CAS DataBase Reference: 1-(2-nitrophenyl)ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-nitrophenyl)ethanamine(100311-54-4)
• EPA Substance Registry System: 1-(2-nitrophenyl)ethanamine(100311-54-4)

Safety Data

• Hazardous Substances Data: 100311-54-4(Hazardous Substances Data)

Usage

Physical State

Solid

Color

Pale yellow

Usage

Intermediate in the production of pharmaceuticals and organic compounds

Functional Group

Nitro group

Reactivity

Reactive due to the presence of the nitro group

Hazard Level

Low hazard chemical

Health Risks

Not known to have significant health risks when handled properly

Environmental Risks

Not known to have significant environmental risks when handled properly

Safety Precautions

Must be handled and used in accordance with proper safety precautions and guidelines.

Upstream product

• 577-59-3 2-acetylnitrobenzene 
• 1262802-04-9 (E)-1-(2-nitrophenyl)ethanone O-methyl oxime 
• 288591-69-5 o-nitroacetophenone O-methyl oxime 

Downstream Products

• 204515-43-5 1-[[1-(2-Nitrophenyl)]ethyl]amino]2'-deoxycarbainosine 
• 1431699-56-7 2-Nitro-α-phenethylamine hydrochloride 
• 917222-59-4 acetic acid 2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{4-[1-(2-nitro-phenyl)-ethylamino]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-3-yl ester 
• 138571-59-2 N-{(S)-1-[1-(2-Nitro-phenyl)-ethylcarbamoyl]-ethyl}-benzamide 

Relevant articles and documents

A versatile new synthetic route to 1 N-hydroxyindazoles

A new and versatile cyclization reaction affording rare 1 JV-hydroxyindazoles Is presented. Treatment of 2-nitrobenzylamines with methanolic sodium hydroxide furnishes 1 N-hydroxylndazoles regloselectively and In high yield. The reaction tolerates a range

DIAMIDE MACROCYCLES AS FACTOR XIA INHIBITORS

The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.