100311-75-9Relevant articles and documents
Total Synthesis of Leukotriene B44> and Homo-LTB4 from D-Mannitol
Merrer, Yves Le,Gravier-Pelletier, Christine,Micas-Languin, Dominique,Mestre, Francoise,Dureault, Annie,Depezay, Jean-Claude
, p. 2409 - 2416 (2007/10/02)
A convergent total synthesis of leukotriene B4 and its homo analogue has been carried out via enantiomerically pure α-hydroxy aldehydes, chiral key intermediates obtained from D-mannitol and connected at a four carbon atom interval by Wittig re
A Chemoenzymatic Synthesis of Leukotriene B4
Han, Chao-Qi,DiTullio, Dennis,Wang, Yi-Fong,Sih, Charles J.
, p. 1253 - 1258 (2007/10/02)
A total synthesis of leukotriene B4 (1) is accomplished by the assembly of the key chirons 2 and 3, which are prepared via enzymatic methods.
