1003444-36-7Relevant articles and documents
Borate esters as convenient reagents for direct amidation of carboxylic acids and transamidation of primary amides
Starkov, Pavel,Sheppard, Tom D.
, p. 1320 - 1323 (2011)
Simple borates serve as effective promoters for amide bond formation with a variety of carboxylic acids and amines. With trimethyl or tris(2,2,2- trifluoroethyl) borate, amides are obtained in good to excellent yield and high purity after a simple work-up procedure. Tris(2,2,2-trifluoroethyl) borate can also be used for the straightforward conversion of primary amides to secondary amides via transamidation. The Royal Society of Chemistry 2011.