100349-05-1Relevant articles and documents
Active site mapping of porcine liver esterase (PLE) and porcine pancreatic lipase (PPL): Stereo and regiochemical outcome of hydrolysis of conformationally constrained esters
Basak,Rudra,Ghosh,Bhattacharya
, p. 974 - 980 (2007/10/03)
The regio and stereoselectivity of PLE and PPL-catalyzed hydrolysis of a number of conformationally constrained substrates have been studied. The results are discussed based on the existing active site models for the two enzymes.
A STEREOCONTROLLED SYNTHESIS OF 3-(1'-HYDROXYETHYL)-2-AZETIDINONES THROUGH TRIMETHYLSILYL TRIFLUOROMETHANESULPHONATE CATALYZED CONDENSATION OF SILYL KETENE ACETAL DERIVED FROM ETHYL 3-HYDROXYBUTYRATE AND IMINE
Guanti, Giuseppe,Narisano, Enrica,Banfi, Luca
, p. 4335 - 4338 (2007/10/02)
The silyl ketene acetal 2, prepared from ethyl 3-hydroxybutyrate, reacted with benzylidene aniline in the presence of trimethylsilyl trifluoromethanesulphonate to furnish in satisfactory yield the β-amino ester 3 as a single diastereomer, which was subseq
Stereoselective Synthesis of 3-(1-Hydroxyethyl)-2-azetidinones from 3-Hydroxybutyrates
Georg, Gunda I.
, p. 3779 - 3782 (2007/10/02)
Addition of dianions of 3-hydroxybutyrates to benzylideneaniline result in direct formation of trans S*-3-(1-hydroxyethyl)-1,4-diphenyl-2-azetidinone with 95percent diastereoselectivity.Inversion of the configuration at Cα gives the