100366-66-3Relevant articles and documents
The Preparation and Co-ordination Chemistry of 2,2':6',2"-Terpyridine Macrocycles. Part 5. Unsubstituted Fifteen-membered-ring Macrocycles containing 2,2':6',2"-Terpyridine
Constable, Edwin C.,Holmes, Jeremy M.,McQueen, Roderick C. S.
, p. 5 - 8 (1987)
The preparation of a simple unsubstituted quinquedentate macrocycle incorporating a 2,2':6',2"-terpyridine moiety by a transient template reaction is described.The cobalt(II), nickel(II), copper(II), and zinc(II) complexes of the ligand are described, as is the oxidation-reduction chemistry of these compounds.E.s.r. studies indicate that pentagonal-bipyramidal complexes, with solvent molecules occupying the axial sites, are formed.
Synthesis of Halogenated Terpyridines and Incorporation of the Terpyridine Nucleus into a Polyetheral Macrocycle
Newkome, George R.,Hager, David C.,Kiefer, Garry E.
, p. 850 - 853 (1986)
Two synthetic approaches to haloterpyridines are herein described.The first method involved direct halogenation of terpyridine N-oxides with POCl3 to generate a mixture of polyhalogenated terpyridines.A more efficient approach to 6,6''-dibromo-2,2':6',2''-terpyridine utilized the Kroehnke synthesis to form the terpyridine moiety from appropriately halosubstituted precursors.Direct nucleophilic substitution on terpyridine was found to give low yields of macrocyclic products; however, if 1,5-bis(6-bromo-2-pyridyl)-1,5-dioxopentane was employed, macrocyclization afforded improved yields of the desired terpyridines.
Synthesis of some 2,2′:6′,2″-terpyridines disubstituted in positions 6 and 6″ with head-to-tail oriented amino acids and dipeptides: A simple entry to a reversible inducer of folding in amino acid sequences
Annunziata, Rita,Benaglia, Maurizio,Puglisi, Alessandra,Raimondi, Laura,Cozzi, Franco
body text, p. 3976 - 3983 (2009/04/10)
The 2,2′:6′,2″-terpyridine scaffold has been identified as a conformationally discrete structural element potentially capable of inducing reversible folding in substituents, attached through suitable spacers to its 6,6″-positions, by metal complexation/de