10037-31-7

Basic information

• Product Name: DIMETHYL 4-METHYL-2,3-QUINOLINEDICARBOXYLATE
• Synonyms: DIMETHYL 4-METHYL-2,3-QUINOLINEDICARBOXYLATE;2,3-dimethyl 4-methylquinoline-2,3-dicarboxylate
• CAS NO: 10037-31-7
• Molecular Formula: C14H13NO4
• Molecular Weight: 259.26
• Mol File: 10037-31-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 97.5-99 °C(Solv: benzene (71-43-2); hexane (110-54-3))
• Boiling Point: 358.7±37.0 °C(Predicted)
• Appearance: /
• Density: 1.241±0.06 g/cm3(Predicted)
• PKA: 0.72±0.50(Predicted)
• CAS DataBase Reference: DIMETHYL 4-METHYL-2,3-QUINOLINEDICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL 4-METHYL-2,3-QUINOLINEDICARBOXYLATE(10037-31-7)
• EPA Substance Registry System: DIMETHYL 4-METHYL-2,3-QUINOLINEDICARBOXYLATE(10037-31-7)

Safety Data

• Hazardous Substances Data: 10037-31-7(Hazardous Substances Data)

Upstream product

• 551-93-9 2-aminoacetophenone 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 2392-68-9 3-chlorophenyl-isothiocyanate 
• 613-89-8 2-Aminoacetophenone 
• 103-84-4 Acetanilid 
• 62-53-3 aniline 
• 20712-09-8 3-methyl-2,1-benzisothiazole 

Relevant articles and documents

Regioselective intramolecular annulations of ambident β-enamino esters: A diversity-oriented synthesis of nitrogen-containing privileged molecules

Diversity-oriented, regioselective, intramolecular annulation of β-enamino esters is described under solvent-free, calcium-catalysis. 2-aminoaryl ketones and alkyl propiolates undergone a [4+2] annulation to yield substituted quinolines; with an excess of

Synthesis of polysubstituted quinolines via copper(ii)-catalyzed annulation of 2-aminoaryl ketones with alkynoates

Copper triflate catalyzed annulation of 2-aminoaryl ketones with internal alkynes has been developed for the synthesis of polysubstituted quinolines in high yields under solvent-free conditions. Phenyl propiolic acid afforded the 3-unsubstituted quinoline

Synthesis of functionalized quinolines and benzo[c][2,7]naphthyridines based on a photo-fries rearrangement

An efficient one-pot method for the synthesis of functionalized quinolines and tetrahydronaphthyridines has been developed. The photo-Fries rearrangement of p-substituted anilides afforded differently substituted o-amino ketones that reacted in situ with acetylenic Michael acceptors such as dimethyl acetylenedicarboxylate (DMAD) to give 6,4-disubstituted quinoline 2,3-dicarboxylates. Starting from anilides derived from β-alanine, a naphthyridine nucleus can also be assembled.