1003843-30-8

Basic information

• Product Name: N-Boc-cis-2,6-Diethyl-4-piperidone
• Synonyms: N-Boc-cis-2,6-Diethyl-4-piperidone;N-boc-2,6-diethyl-4-oxo-piperdine;cis-2,6-Diethyl-4-oxopiperidine-1-carboxylic acid tert-butyl ester;tert-Butyl 2,6-diethyl-4-oxopiperidine-1-carboxylate;1-Piperidinecarboxylicacid, 2,6-diethyl-4-oxo-, 1,1-diMethylethyl ester, (2R,6S)-rel-;cis-2,6-Diethyl-4-oxo-1-piperidinecarboxylic acid, 1,1-diMethylethyl ester;(2R,6S)-rel-tert-Butyl 2,6-diethyl-4-oxopiperidine-1-carboxylate;tert-butyl (2R,6S)-2,6-diethyl-4-oxopiperidine-1-carboxylate
• CAS NO: 1003843-30-8
• Molecular Formula: C₁₄H₂₅NO₃
• Molecular Weight: 255.3532
• Mol File: 1003843-30-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 340.907 °C at 760 mmHg
• Flash Point: 159.975 °C
• Appearance: /
• Density: 0.996
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-Boc-cis-2,6-Diethyl-4-piperidone(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-cis-2,6-Diethyl-4-piperidone(1003843-30-8)
• EPA Substance Registry System: N-Boc-cis-2,6-Diethyl-4-piperidone(1003843-30-8)

Safety Data

• Hazardous Substances Data: 1003843-30-8(Hazardous Substances Data)

Usage

General Description

N-Boc-cis-2,6-Diethyl-4-piperidone is a chemical compound with the molecular formula C15H27NO3. It is a piperidone derivative that contains a Boc protecting group and two ethyl substituents at the 2 and 6 positions of the piperidone ring. N-Boc-cis-2,6-Diethyl-4-piperidone is commonly used as a building block in organic synthesis, particularly in the pharmaceutical industry for the preparation of various drug molecules. It can undergo various chemical reactions, such as substitution, oxidation, and reduction, to yield a wide range of derivatives with diverse biological activities. N-Boc-cis-2,6-Diethyl-4-piperidone has potential applications in medicinal chemistry and drug discovery as a versatile intermediate for the synthesis of therapeutic agents.

Upstream product

• 1148130-16-8 tert-butyl 2, 6-diethyl-4-oxopiperidine-1-carboxylate 
• 1003843-25-1 rac-tert-butyl 2-ethyl-4-oxo-3,4-dihydropyridine-1(2H)-carboxylate 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 1148130-18-0 tert-butyl (2R,4r,6S)-4-(benzylamino)-2,6-diethylpiperidine-1-carboxylate 
• 1149362-88-8 (1r,4r)-4-(((2R,4r,6S)-4-((3,5-bis(trifluoromethyl)benzyl)(5-(1-methyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)-2,6-diethylpiperidine-1-carbonyl)oxy)cyclohexane-1-carboxylic acid 
• 1148129-86-5 tert-butyl (2R,4r,6S)-4-((3,5-bis(trifluoromethyl)benzyl)(5-bromopyrimidin-2-yl)amino)-2,6-diethylpiperidine-1-carboxylate 
• 1148129-85-4 tert-butyl (2R,4r,6S)-4-((3,5-bis(trifluoromethyl)benzyl)(5-morpholinopyrimidin-2-yl)amino)-2,6-diethylpiperidine-1-carboxylate 
• 1148129-88-7 tert-butyl (2R,4r,6S)-4-((3,5-bis(trifluoromethyl)benzyl)(5-(1-methyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)-2,6-diethylpiperidine-1-carboxylate 
• 1148129-44-5 (1r,4r)-4-(methoxycarbonyl)cyclohexyl (2R,4r,6S)-4-((3,5-bis-(trifluoromethyl)benzyl)(5-morpholinopyrimidin-2-yl)amino)-2,6-diethylpiperidine-1-carboxylate 
• 1148129-95-6 N-(3,5-bis-(trifluoromethyl)benzyl)-N-((2R,4r,6S)-2,6-diethylpiperidin-4-yl)-5-(1-methyl-1H-pyrazol-4-yl)pyrimidin-2-amine 
• 1149362-89-9 (1r,4r)-4-(methoxycarbonyl)-cyclohexyl (2R,4r,6S)-4-((3,5-bis(trifluoromethyl)benzyl)(5-(1-methyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)-2,6-diethylpiperidine-1-carboxylate 

Relevant articles and documents

ORGANIC COMPOUNDS

The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R5, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.