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CAS

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100490-36-6

TOSUFLOXACIN TOSILATE, with the CAS number 100490-36-6, is an active pharmaceutical ingredient that belongs to the class of fluoroquinolone antibiotics. It is known for its broad-spectrum antimicrobial activity and is effective against a variety of bacterial infections.

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  • 100490-36-6 Structure

  • Basic information

    1. Product Name: TOSUFLOXACIN TOSILATE
    2. Synonyms: 1,8-naphthyridine-3-carboxylicacid,1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-(;4-difluorophenyl)-6-fluoro-4-oxo-;a61827;a67107;abbott61827;1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-aminopyrrolidin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid;1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo- (9CI);(+)-7-(3-Amino-1-pyrrolidinyl)-6-fluoro-1-(2，4-difluo-rophenyl)-1，4-dihydrcr-4-oxo-1，8-naphthyridine-3-carboxyli cacid
    3. CAS NO:100490-36-6
    4. Molecular Formula: C19H15F3N4O3
    5. Molecular Weight: 576.54
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 100490-36-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 614.4 °C at 760 mmHg
    3. Flash Point: 325.4 °C
    4. Appearance: White powder
    5. Density: 1.558 g/cm3
    6. Vapor Pressure: 5.96E-16mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 5.79±0.70(Predicted)
    11. CAS DataBase Reference: TOSUFLOXACIN TOSILATE(CAS DataBase Reference)
    12. NIST Chemistry Reference: TOSUFLOXACIN TOSILATE(100490-36-6)
    13. EPA Substance Registry System: TOSUFLOXACIN TOSILATE(100490-36-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 100490-36-6(Hazardous Substances Data)

100490-36-6 Usage

Uses

Used in Pharmaceutical Industry:
TOSUFLOXACIN TOSILATE is used as an antibiotic for treating bacterial infections. It works by inhibiting bacterial DNA replication and protein synthesis, leading to the disruption of bacterial cell function and ultimately resulting in cell death. This makes it a valuable component in the development of medications aimed at combating various bacterial pathogens.
Used in Antimicrobial Research:
In the field of antimicrobial research, TOSUFLOXACIN TOSILATE is utilized for studying its effectiveness against different strains of bacteria, such as the Haemophilus influenza clone ST422 mentioned in the provided materials. This research helps in understanding the antibiotic's potential applications and limitations in treating specific bacterial infections, contributing to the development of more targeted and effective treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 100490-36-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,9 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100490-36:
(8*1)+(7*0)+(6*0)+(5*4)+(4*9)+(3*0)+(2*3)+(1*6)=76
76 % 10 = 6
So 100490-36-6 is a valid CAS Registry Number.
InChI:InChI=1/C19H15F3N4O3.C7H8O3S/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25;1-6-2-4-7(5-3-6)11(8,9)10/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29);2-5H,1H3,(H,8,9,10)

100490-36-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name TOSUFLOXACIN TOSILATE

1.2 Other means of identification

Product number -
Other names 1,8-NAPHTHYRIDINE-3-CARBOXYLICACID,7-(3-AMINO-1-PYRROLIDINYL)-1-(2,4-DIFLUOROPHENYL)-6-FLUORO-1,4-DIHYDRO-4-OXO-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100490-36-6 SDS

100490-36-6Upstream product

100490-36-6Downstream Products

100490-36-6Relevant articles and documents

Naphthyridine antianaerobic compounds

-

, (2008/06/13)

The naphthyridine compounds having the formula: wherein R1 is hydrogen or a carboxy protecting group have unexpected and superior antianaerobic activity.

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