100669-01-0

Basic information

• Product Name: Benzene, [[(2,2-dimethyl-6-methylenecyclohexyl)methyl]sulfonyl]-
• CAS NO: 100669-01-0
• Molecular Formula: C16H22O2S
• Molecular Weight: 278.415
• Mol File: 100669-01-0.mol

Chemical Properties

• CAS DataBase Reference: Benzene, [[(2,2-dimethyl-6-methylenecyclohexyl)methyl]sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [[(2,2-dimethyl-6-methylenecyclohexyl)methyl]sulfonyl]-(100669-01-0)
• EPA Substance Registry System: Benzene, [[(2,2-dimethyl-6-methylenecyclohexyl)methyl]sulfonyl]-(100669-01-0)

Safety Data

• Hazardous Substances Data: 100669-01-0(Hazardous Substances Data)

Upstream product

• 25996-10-5 (Z)-neryl bromide 
• 106-25-2 Nerol 
• 56881-52-8 (Z)-(3,7-dimethylocta-2,6-diene-1-sulfonyl)benzene 
• 56691-80-6 geranyl phenyl sulfone 
• 88218-61-5 2,2-dimethyl-6-methylene-1-phenylthiomethylcyclohexane 

Downstream Products

• 88253-09-2 (E,E)-9-(2',2'-dimethyl-6'-methylenecyclohexanyl)-3,7-dimethyl-9-phenylsulphonyl-2,6-nonadien-1-ol 
• 88218-58-0 (E,E)-9-(2',2'-dimethyl-6'-methylenecyclohexanyl)-3,7-dimethyl-2,6-nonadien-1-ol (trixagol) 

Relevant articles and documents

Superacidic low temperature cyclization of terpenylphenyisulfones

The superacidic cyclization of aliphatic and partially cyclized C10- C20 terpenylphenylsulfones proceeds structure-selectively and stereospecifically, affording α- or mixtures of α- and γ-isomers of completely cyclized terpenylphenylsulfones. The configuration of the phenylsuffonylmethylene group in the cyclized products is predetermined by the configuration of the allylic double bond in the starting compounds.

Synthesis of (+/-)-trixagol by an electrophilic cyclization of an allylsilane

1,5-Dienes containing an allylsilane are cyclized by Lewis acids to methylenecyclohexanes.The trimethylsilyl group exerts a strong activating and directing influence on the regioselectivity of this cyclization.The monocyclic compound 10 was converted into the diterpene, (+/-)-trixagol (3).