100726-39-4

Basic information

• Product Name: (2-PYRIDIN-2-YL-BENZOIMIDAZOL-1-YL)-ACETIC ACID
• Synonyms: BAS 13050037;ST5294845;(2-PYRIDIN-2-YL-BENZOIMIDAZOL-1-YL)-ACETIC ACID;ASINEX-REAG BAS 13050037;[2-(2-Pyridinyl)-1H-benzimidazol-1-yl]acetic acid;(2-pyridin-2-yl-1H-benzimidazol-1-yl)acetic acid;2-(2-pyridin-2-ylbenzimidazol-1-yl)acetic acid;2-(2-pyridin-2-ylbenzimidazol-1-yl)ethanoic acid
• CAS NO: 100726-39-4
• Molecular Formula: C14H11N3O2
• Molecular Weight: 253.26
• Mol File: 100726-39-4.mol

Chemical Properties

• Boiling Point: 531.1±56.0 °C(Predicted)
• Appearance: /
• Density: 1.35±0.1 g/cm3(Predicted)
• PKA: 3.00±0.10(Predicted)
• CAS DataBase Reference: (2-PYRIDIN-2-YL-BENZOIMIDAZOL-1-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2-PYRIDIN-2-YL-BENZOIMIDAZOL-1-YL)-ACETIC ACID(100726-39-4)
• EPA Substance Registry System: (2-PYRIDIN-2-YL-BENZOIMIDAZOL-1-YL)-ACETIC ACID(100726-39-4)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25-37/38-41
• Safety Statements: 26-39-45
• HazardClass: IRRITANT
• Hazardous Substances Data: 100726-39-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(2-PYRIDIN-2-YL-BENZOIMIDAZOL-1-YL)-ACETIC ACID is used as an enzyme inhibitor for its ability to modulate the activity of specific enzymes involved in various biological processes. This makes it a promising candidate for the development of drugs targeting enzyme-related diseases.
Used in Medicinal Applications:
In the field of medicine, (2-PYRIDIN-2-YL-BENZOIMIDAZOL-1-YL)-ACETIC ACID is utilized as a potential therapeutic agent for the treatment of various diseases. Its chemical structure allows it to interact with specific biological targets, offering a new avenue for the treatment of conditions that may not be effectively addressed by existing medications.
Used in Research and Development:
(2-PYRIDIN-2-YL-BENZOIMIDAZOL-1-YL)-ACETIC ACID is employed in research and development efforts within the pharmaceutical industry. Its unique properties and potential applications make it an important compound for exploring new drug targets and developing innovative therapeutic strategies.

Upstream product

• 1137-68-4 2-(2'-pyridyl)benzimidazole 
• 74356-96-0 (2-[2]pyridyl-benzimidazol-1-yl)-acetic acid methyl ester 

Relevant articles and documents

Ruthenium complexes of 2-(2′-pyridyl)benzimidazole as photosensitizers for dye-sensitized solar cells

N-Alkylated carboxylic acid derivatives of 2-(2′-pyridyl)benzimidazole (pbimH) with different chain-lengths (pbim(CH)nCO2H where n = 1-3) and their ruthenium complexes [Ru(bpy)2(pbim)](PF6)2 have been synthesized and characterized. 2D COSY and NOESY NMR spectroscopy were used to aid the assignment of the pbim NMR spectrum. The effect of chain-length on the cyclic voltammetry (CV) was studied and the voltammetry of the parent pbimH complex was re-investigated. The ability of the carboxylic acid groups to bind to TiO2 coated electrodes was confirmed by the observation of a symmetrical, surface-confined RuIII/II wave, while the specular reflectance IR revealed a band at 1620 cm-1 due to the bound carboxylate (COO ... Ti) group. The efficiencies of solar cells using these sensitizers were rather low, due to the distance between the sensitizer and the surface and the inefficient coupling of the charge-separated excited state to the surface. A fall in the cell open-circuit voltage with chain length reflected this distance effect. Time-resolved luminescence spectroscopy indicated that rapid electron injection into the TiO2 conduction band was occurring (30 ns), but this is not fast enough to compete effectively with alternative excited state processes.