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1009092-91-4

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1009092-91-4 Usage

General Description

Tert-butyl (4R,5R)-4-(hydroxymethyl)-2,2-dimethyl-5-phenyl-1,3-oxazolidine-3-carboxylate is a chemical compound that contains a tert-butyl group, a hydroxymethyl group, a dimethyl group, a phenyl group, and an oxazolidine-3-carboxylate group. tert-butyl (4R,5R)-4-(hydroxymethyl)-2,2-dimethyl-5-phenyl-1,3-oxazolidine-3-carboxylate has a specific stereochemistry, with the 4R and 5R configurations, giving it a unique spatial arrangement. It is often used in organic synthesis as a chiral building block for the preparation of complex molecules. tert-butyl (4R,5R)-4-(hydroxymethyl)-2,2-dimethyl-5-phenyl-1,3-oxazolidine-3-carboxylate has potential applications in the pharmaceutical industry for the development of new drugs and therapeutics.

Check Digit Verification of cas no

The CAS Registry Mumber 1009092-91-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,9,0,9 and 2 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1009092-91:
(9*1)+(8*0)+(7*0)+(6*9)+(5*0)+(4*9)+(3*2)+(2*9)+(1*1)=124
124 % 10 = 4
So 1009092-91-4 is a valid CAS Registry Number.

1009092-91-4Relevant articles and documents

Discovery of benzamides as potent human β3 adrenergic receptor agonists

Zhu, Cheng,Kar, Nam F.,Li, Bing,Costa, Melissa,Dingley, Karen H.,Di Salvo, Jerry,Ha, Sookhee N.,Hurley, Amanda L.,Li, Xiaofang,Miller, Randy R.,Salituro, Gino M.,Struthers, Mary,Weber, Ann E.,Hale, Jeffrey J.,Edmondson, Scott D.

, p. 55 - 59 (2015/12/18)

The paper will describe the synthesis and SAR studies that led to the discovery of benzamide (reverse amide) as potent and selective human β3-adrenergic receptor agonist. Based on conformationally restricted pyrrolidine scaffold we discovered e

A process for producing an intermediate agonist GRK 3

-

, (2016/10/09)

The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions.

Asymmetric synthesis of cis-2,5-disubstituted pyrrolidine, the core scaffold of β3-AR agonists

Xu, Feng,Chung, John Y. L.,Moore, Jeffery C.,Liu, Zhuqing,Yoshikawa, Naoki,Hoerrner, R. Scott,Lee, Jaemoon,Royzen, Maksim,Cleator, Ed,Gibson, Andrew G.,Dunn, Robert,Maloney, Kevin M.,Alam, Mahbub,Goodyear, Adrian,Lynch, Joseph,Yasuda, Nobuyashi,Devine, Paul N.

supporting information, p. 1342 - 1345 (2013/04/24)

A practical, enantioselective synthesis of cis-2,5-disubstituted pyrrolidine is described. Application of an enzymatic DKR reduction of a keto ester, which is easily accessed through a novel intramolecular N→C benzoyl migration, yields syn-1,2-amino alcoh

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