1009582-56-2

Basic information

• Product Name: 2,4-DibroMo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-iMidazol-2-yl]Methyl][(S)-1-phenylethyl]aMino]Methyl]phenol
• Synonyms: 2,4-DibroMo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-iMidazol-2-yl]Methyl][(S)-1-phenylethyl]aMino]Methyl]phenol;2,4-Dibromo-6-[[[[(4S,5S)-4,5-dihydro-1-[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1H-imidazol-2-yl]methyl][(1S)-1-phenylethyl]amino]methyl]phenol
• CAS NO: 1009582-56-2
• Molecular Formula: C₃₈H₃₅Br₂N₃O₃S
• Molecular Weight: 773.5758
• Mol File: 1009582-56-2.mol

Chemical Properties

• Boiling Point: 772.9±70.0 °C(Predicted)
• Appearance: /
• Density: 1.43±0.1 g/cm3(Predicted)
• Storage Temp.: <0°C
• PKA: 7.71±0.48(Predicted)
• CAS DataBase Reference: 2,4-DibroMo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-iMidazol-2-yl]Methyl][(S)-1-phenylethyl]aMino]Methyl]phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DibroMo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-iMidazol-2-yl]Methyl][(S)-1-phenylethyl]aMino]Methyl]phenol(1009582-56-2)
• EPA Substance Registry System: 2,4-DibroMo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-iMidazol-2-yl]Methyl][(S)-1-phenylethyl]aMino]Methyl]phenol(1009582-56-2)

Safety Data

• Hazardous Substances Data: 1009582-56-2(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2,4-Dibromo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-imidazol-2-yl]methyl][(S)-1-phenylethyl]amino]methyl]phenol is used as a catalyst in chemical synthesis, particularly for reactions involving the formation of carbon-carbon or carbon-heteroatom bonds. Its unique structure allows it to facilitate and enhance the rate of these reactions, improving the overall efficiency and yield of the synthesized products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,4-Dibromo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-imidazol-2-yl]methyl][(S)-1-phenylethyl]amino]methyl]phenol is utilized as a catalyst for the synthesis of various drug molecules. Its ability to accelerate and control the course of chemical reactions can lead to the development of new and improved pharmaceutical compounds with enhanced efficacy and reduced side effects.
Used in Material Science:
2,4-Dibromo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-imidazol-2-yl]methyl][(S)-1-phenylethyl]amino]methyl]phenol also finds application in the field of material science, where it is employed as a catalyst for the synthesis of advanced materials with specific properties. These materials can be used in various applications, such as electronics, energy storage, and environmental protection.
Used in Environmental Applications:
In environmental applications, 2,4-Dibromo-6-[[[[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-imidazol-2-yl]methyl][(S)-1-phenylethyl]amino]methyl]phenol is used as a catalyst for the degradation of pollutants and contaminants. Its catalytic properties enable the efficient breakdown of harmful substances, contributing to a cleaner and more sustainable environment.

Upstream product

• 90-59-5 3,5-Dibromosalicylaldehyde 
• 1009582-71-1 (1S)-N-{[(4S,5S)-4,5-dihydro-4,5-diphenyl-1-tosyl-1H-imidazol-2-yl]methyl}-1-phenylethanamine 

Relevant articles and documents

A library of chiral imidazoline-aminophenol ligands: Discovery of an efficient reaction sphere

A library of imidazolineaminophenol ligands was synthesized on solid supports. After immobilization of chiral chloromethylimidazolines 1 and 2 onto the polystyrylsulfonyl chloride, nucleophilic substitution with (R)-or (S)-phenylethylamine (3 and 4) provided four combinations of polymersupported imidazoline-amine ligands. Further reductive alkylation using salicylaldehydes 7-10 provided a series of imidazoline-aminophenol ligands (L9-L24). Analysis by solid-phase catalysis/circular dichroism high-throughput screening of a copper-catalyzed Henry reaction revealed that ligand L25, comprising a (5,5)-diphenylethylenediamine-derived imidazoline, (S)-phenylethylamine, and dibromophenol, was highly efficient, thus providing the adduct of nitromethane and benzaldehyde in 95 % ee. The combination of stereogenic centers was crucial in promoting the highly stereoselective reactions. The unique reaction sphere of L25 was also examined in a Friedel-Crafts alkylation of indole and nitroalkene to give the adduct in up to 83% ee.

Asymmetric Friedel-Crafts reaction of N-heterocycles and nitroalkenes catalyzed by imidazoline-aminophenol-Cu complex

Catalytic asymmetric Friedel-Crafts reaction of pyrrole with nitroalkenes was smoothly catalyzed by newly synthesized nitro-substituted imidazoline-aminophenol (1b)-Cu complex to give the adduct with up to 92% ee.