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Cas Database

10098-89-2

10098-89-2

Identification

  • Product Name:L-Lysine hydrochloride

  • CAS Number: 10098-89-2

  • EINECS:233-234-9

  • Molecular Weight:182.65

  • Molecular Formula: C6H15N2O2*Cl

  • HS Code:2922419000

  • Mol File:10098-89-2.mol

Synonyms:L-LYSINE HYDROCHLORIDE SOLUTION; (L)-lysine monohydrochloride; L-LYSINEHCL(FEED); L-Lysine/hydrochloric acid,(1:x); anhydrous L-lysine monohydrochloride; (2S)-2,6-bis(azanyl)hexanoic acid hydrochloride; (S)-2,6-Diaminohexanoic acid monohydrochloride; H-Lys-OH hydrochloride; L-Lysine hydrochlori; 查看更多英文别名 收起

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Safety information and MSDS view more

  • Signal Word:no data available

  • Hazard Statement:no data available

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. /SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
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  • Manufacture/Brand:Usbiological
  • Product Description:L-Lysine Hydrochloride
  • Packaging:100g
  • Price:$ 47
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:L-Lysine hydrochloride United States Pharmacopeia (USP) Reference Standard
  • Packaging:200 mg
  • Price:$ 429
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:L-Lysine hydrochloride solution 100mM amino acid in 0.1 M HCl, analytical standard
  • Packaging:5ml-f
  • Price:$ 63.2
  • Delivery:In stock
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Relevant articles and documentsAll total 7 Articles be found

A Water-Soluble Cationic Zinc Lysine Precursor for Coating ZnO on Biomaterial Surfaces

Yuan, Shaotang,Nawrocki, Shiri,Stranick, Michael,Yang, Ying,Zheng, Chong,Masters, James G.,Pan, Long

, p. 10094 - 10097 (2016)

A novel water-soluble cationic zinc lysine coordination compound, [Zn[(C6H14N2O2)]2Cl]Cl·2H2O (1), has been designed and synthesized and its crystal structure determined. The aqueous solution of this coordination compound is not only transparent and stable at room temperature but it is also nearly neutral (pH ~ 7). It is worth noting that zinc oxide (ZnO) forms in situ upon dilution of a solution of the compound. The bioactivity of ZnO has been confirmed using an Alarma Blue assay. These unique properties allow the coordination compound to gently grow ZnO coating with excellent antibacterial benefits onto biomaterial surfaces in a facile and safe manner.

Chiral Receptors for Lysine Based on Covalently Linked Bis- and Tris-binaphthylphosphoric Acids

Octa-Smolin, Frescilia,Thiele, Maike,Yadav, Rohan,Platzek, André,Clever, Guido H.,Niemeyer, Jochen

supporting information, p. 6153 - 6156 (2018/10/05)

The synthesis and application of three chiral receptors based on the covalent linkage of 1,1′-binaphthylphosphoric acids is reported. The binding of the lysine enantiomers to the chiral receptors was investigated by DOSY-NMR and NMR titrations, revealing that the bisphosphoric acid 1d acts as a highly stereoselective receptor for binding of d-lysine.

Polyunsaturated fatty acid derivatives, pharmaceutical compositions containing the same, method for the preparation thereof, and their use as medicament

-

, (2008/06/13)

The compounds of the Formula (I) STR1 wherein R1 is a C18-24 alkenyl containing at least two double bonds, or --(CH2)n --CH(NH2)m --COOH X is 0, NH or C1-4 alkyl-N, Y is CONH2, COOH or COOMe, wherein Me is hydrogen metal, and R2 is a side chain of a any amino acid except L-GLU or L-ASP at α-position or a group of Formula wherein k is zero or an integer of 1, n is zero or an integer of 1 to 3, m is zero or an integer of 1 to 4, A is hydroxyl or one A is hydroxyl and the other A is hydrogen. M is H or R1 --CO and X and R1 are as defined above and their salts having tyrosine kinase inhibitor activity can be used as antitumor agents.

Sesquiterpene compounds and pharmaceutical compositions containing same, from pachastrella sponges

-

, (2008/06/13)

A new class of novel, biologically active sesquiterpene compounds, pharmaceutical compositions containing them, methods of producing the compounds and compositions and methods of using them are disclosed. This new class of compounds have the generic formulae: STR1 and R1, R2, R3, R4, R5, R6, R7 =H or lower alkyl.

Enantioselective synthesis of isotopically labelled α-amino acids. Preparation of (ε-13C)-L-α-aminoadipic acid and five isotopomers of L-lysine with 13C, 15N and 2H in the δ and ε-positions

Raap, J.,Wielen, C. M. van der,Lugtenburg, J.

, p. 277 - 286 (2007/10/02)

An asymmetric synthesis of the six-carbon α-amino acids (ε-13C)-L-α-aminoadipic acid and various isotopomers of L-lysine is described.The synthesis is based on a general method starting from the bis-lactim ether of cyclo(D-Val-Gly) and simple labelled reagents like K(13)CN, K(13)C15N, (13)CH3CN and LiAl(2)H4.Using this route (ε-13C)-L-α-aminoadipic acid was prepared in 31percent yield based on the labelled potassium cyanide.Five different isotopomers of L-lysine were prepared in high overall yield (45percent based on the labelled starting compound): (ε-13C)-L-lysine,(ε-13C,ε-15N)-L-lysine, (δ-13C)-L-lysine, (ε-2H2)-L-lysine and (ε-13C,ε-2H2)-L-lysine.The isotopomers were characterized using various spectroscopic techniques, e.g., 1H NMR, 2H NMR, 13C NMR, 15N NMR and mass spectrometry.The 31.2-ppm and the 27.6-ppm peak in the 13C NMR spectrum of lysine could be unambiguously assigned to the β- and δ-carbons, respectively.This means that the assignment previously reported is incorrect.

Process route upstream and downstream products

Process route

Conditions
Conditions Yield
at 30 ℃; for 72h; Yield given. Further byproducts given. Yields of byproduct given; Brevibacterium flavum, mutant strain AH-198, soybean-meal hydrolysate, (NH4)2SO4;
N-acetyl-cyclolysine
118477-18-2

N-acetyl-cyclolysine

L-Lysine hydrochloride
657-27-2,10098-89-2,26124-78-7

L-Lysine hydrochloride

Conditions
Conditions Yield
With hydrogenchloride; for 5.5h; Heating;
100%
4-<(2R,5S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxy-5-pyrazinyl>butylamine
129243-87-4

4-<(2R,5S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxy-5-pyrazinyl>butylamine

L-Lysine hydrochloride
657-27-2,10098-89-2,26124-78-7

L-Lysine hydrochloride

Conditions
Conditions Yield
With hydrogenchloride; at 70 ℃;
80%
With hydrogenchloride; at 70 ℃;
Isobengamide E
118477-05-7

Isobengamide E

L-Lysine hydrochloride
657-27-2,10098-89-2,26124-78-7

L-Lysine hydrochloride

Conditions
Conditions Yield
Multi-step reaction with 2 steps
2: 100 percent / aq. HCl / 5.5 h / Heating
With hydrogenchloride;
4-<(2R,5S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxy-5-pyrazinyl>butyronitrile
129243-83-0

4-<(2R,5S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxy-5-pyrazinyl>butyronitrile

L-Lysine hydrochloride
657-27-2,10098-89-2,26124-78-7

L-Lysine hydrochloride

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 95 percent / LiAlH4 / diethyl ether / 1.5 h / Ambient temperature
2: 80 percent / 6N HCl / 70 °C
With hydrogenchloride; lithium aluminium tetrahydride; In diethyl ether;
C<sub>12</sub>H<sub>28</sub>ClN<sub>4</sub>O<sub>4</sub>Zn<sup>(1+)</sup>*Cl<sup>(1-)</sup>*2H<sub>2</sub>O

C12H28ClN4O4Zn(1+)*Cl(1-)*2H2O

water
7732-18-5

water

L-Lysine hydrochloride
657-27-2,10098-89-2,26124-78-7

L-Lysine hydrochloride

zinc(II) oxide

zinc(II) oxide

Conditions
Conditions Yield
at 37 ℃; for 0.5h; pH=7.4;
L-Lysine hydrochloride
657-27-2,10098-89-2,26124-78-7

L-Lysine hydrochloride

Conditions
Conditions Yield
Conditions
Conditions Yield
With hydrogenchloride; In tetrahydrofuran; water; for 3h;
94.6%
Conditions
Conditions Yield
With hydrogenchloride; (S)-1-phenyl-ethylamine; hydrogen; palladium dichloride; Product distribution; 1.) DME, 20 deg C, 5 h;
S-ethyl trifluoroacetate
383-64-2

S-ethyl trifluoroacetate

L-Lysine hydrochloride
657-27-2,10098-89-2,26124-78-7

L-Lysine hydrochloride

(S)-6-trifluoroacetylamino-2-aminohexanoic acid
10009-20-8,96193-68-9

(S)-6-trifluoroacetylamino-2-aminohexanoic acid

Conditions
Conditions Yield
With sodium hydroxide;

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