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3,3,5,5-Tetramethyl-1-pyrroline N-oxide (TMPO) is a pyrroline-based N-oxyl spin trap, characterized by its white to light yellow adhering crystalline chunks. It is used as a cell-permeable spin trap probe for electron spin resonance (ESR) studies of biological systems, allowing for the detection and analysis of free radicals and other reactive species in various applications.

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  • 10135-38-3 Structure
  • Basic information

    1. Product Name: 3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE
    2. Synonyms: TMPO;3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE;3,3,5,5-TETRAMETHYL-PYRROLINE-N-OXIDE;M4PO;3,3,5,5-Tetramethyl-1-pyrolline-N-oxide;1-Oxylato-3,3,5,5-tetramethyl-4,5-dihydro-3H-pyrrole-1-ium;3,3,5,5-Tetramethyl-1-pyrroline 1-oxide;3,3,5,5-Tetramethyl-4,5-dihydro-3H-pyrrole 1-oxide
    3. CAS NO:10135-38-3
    4. Molecular Formula: C8H15NO
    5. Molecular Weight: 141.21
    6. EINECS: N/A
    7. Product Categories: Analytical Chemistry;ESR Spectrometry;Spin Trapping Reagents;Building Blocks;Heterocyclic Building Blocks;Pyrrolines
    8. Mol File: 10135-38-3.mol
  • Chemical Properties

    1. Melting Point: 58-61 °C(lit.)
    2. Boiling Point: 73 °C1 mm Hg(lit.)
    3. Flash Point: 113.3 °C
    4. Appearance: white to light yellow adhering crystalline chunks
    5. Density: 0.9938 (rough estimate)
    6. Vapor Pressure: 0.0332mmHg at 25°C
    7. Refractive Index: 1.4610 (estimate)
    8. Storage Temp.: 0-6°C
    9. Solubility: N/A
    10. PKA: 2.50±0.60(Predicted)
    11. CAS DataBase Reference: 3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE(10135-38-3)
    13. EPA Substance Registry System: 3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE(10135-38-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: 24/25
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 10135-38-3(Hazardous Substances Data)

10135-38-3 Usage

Uses

Used in Pharmaceutical and Biomedical Research:
TMPO is used as a cell-permeable spin trap probe for ESR studies in pharmaceutical and biomedical research. It helps in the detection and analysis of free radicals and other reactive species, which are crucial for understanding the mechanisms of various diseases and the effectiveness of potential treatments.
Used in Environmental and Analytical Chemistry:
In environmental and analytical chemistry, 3,3,5,5-tetramethyl-1-pyrroline N-oxide is used as a spin trap for the identification and quantification of reactive species in various samples. This aids in assessing the environmental impact of pollutants and the development of effective remediation strategies.
Used in Material Science:
In material science, TMPO is employed as a spin probe to study the behavior of free radicals in different materials. This information is valuable for improving the properties of materials and developing new materials with enhanced performance characteristics.
Overall, 3,3,5,5-tetramethyl-1-pyrroline N-oxide plays a significant role in various scientific fields, providing valuable insights into the behavior of free radicals and other reactive species, which can contribute to the development of new treatments, environmental strategies, and materials with improved properties.

Check Digit Verification of cas no

The CAS Registry Mumber 10135-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,3 and 5 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10135-38:
(7*1)+(6*0)+(5*1)+(4*3)+(3*5)+(2*3)+(1*8)=53
53 % 10 = 3
So 10135-38-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H15NO/c1-7(2)5-8(3,4)9(10)6-7/h6H,5H2,1-4H3

10135-38-3 Well-known Company Product Price

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  • Aldrich

  • (244007)  3,3,5,5-Tetramethyl-1-pyrrolineN-oxide  95%

  • 10135-38-3

  • 244007-250MG

  • 1,210.95CNY

  • Detail

10135-38-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2,4,4-tetramethyl-1-oxido-3H-pyrrol-1-ium

1.2 Other means of identification

Product number -
Other names 3,3,5,5-Tetramethyl-1-pyrroline N-oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10135-38-3 SDS

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