10143-54-1

Basic information

• Product Name: 3-[2-(2-Hydroxyethoxy)ethoxy]propanenitrile
• Synonyms: 3-[2-(2-Hydroxyethoxy)ethoxy]propanenitrile;Brn 1764568;Diethylene glycol mono-2-cyanoethyl ether;Propanenitrile, 3-(2-(2-hydroxyethoxy)ethoxy)-;Propionitrile, 3-(2-(2-hydroxyethoxy)ethoxy)-
• CAS NO: 10143-54-1
• Molecular Formula: C₇H₁₃NO₃
• Molecular Weight: 159.21
• EINECS: 600-212-9
• Mol File: 10143-54-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 284.67°C (rough estimate)
• Flash Point: 143.8°C
• Appearance: /
• Density: 1.0890
• Vapor Pressure: 4.09E-05mmHg at 25°C
• Refractive Index: 1.4452 (estimate)
• CAS DataBase Reference: 3-[2-(2-Hydroxyethoxy)ethoxy]propanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[2-(2-Hydroxyethoxy)ethoxy]propanenitrile(10143-54-1)
• EPA Substance Registry System: 3-[2-(2-Hydroxyethoxy)ethoxy]propanenitrile(10143-54-1)

Safety Data

• Hazardous Substances Data: 10143-54-1(Hazardous Substances Data)

Usage

General Description

3-[2-(2-Hydroxyethoxy)ethoxy]propanenitrile is a chemical compound with the molecular formula C8H15NO3. It is a nitrile, which means it contains a carbon triple-bonded to a nitrogen atom. The compound contains three ethoxy groups connected to a propane backbone. It is commonly used as a solvent in various industries, and it is also used in the synthesis of other chemicals. It is important to handle this compound with caution, as it can be harmful if ingested, inhaled, or comes into contact with the skin. Proper safety measures should be taken when working with this chemical.

InChI:InChI=1/C7H13NO3/c8-2-1-4-10-6-7-11-5-3-9/h9H,1,3-7H2

Upstream product

• 107-13-1 acrylonitrile 
• 111-46-6 diethylene glycol 
• 22397-31-5 bis(2-(2-cyanoethoxy)ethyl)ether 
• 542-76-7 3-Chloropropionitrile 

Downstream Products

• 4246-51-9 4,7,10-trioxa-1,13-diaminotridecane 
• 112-33-4 2-[2-(3-amino-propoxy)-ethoxy]-ethanol 
• 111-46-6 diethylene glycol 

Relevant articles and documents

Target protein degradation inducing compound, preparation method thereof and pharmaceutical composition for preventing or treating targeted protein related diseases containing the same as an active ingredient

The present invention relates to a degraducer for inducing the decomposition of target protein, a producing method thereof, and a pharmaceutical composition for preventing or treating target protein-related diseases by containing the degraducer as an active ingredient. A novel compound represented by chemical formula 1, ULB-L-PTM, by the present invention, as a degraducer compound inducing the decomposition of target protein using cereblon E3 ubiquitin ligase, is able to significantly achieve a target protein degradation-inducing activity with an excellent binding activity of a cereblon E3 ubiquitin ligase binder thereby, being able to achieve an excellent protein degradation activity by targeting protein or polypeptide related to various diseases. The bromodomain-containing pharmaceutical composition for preventing or treating protein-related diseases or conditions contains the novel compound represented by chemical formula 1 as an active ingredient and has a useful effect of providing a health functional food composition for prevention or improvement.(AA) Example 22 (nM, 24h)COPYRIGHT KIPO 2020

Aminopropylation of alcohols in the presence of amide or ether solvents

This invention relates to an improved hydrogenation process for the preparation of etheramines. In the process, cyanoethylated alcohols, i.e., the reaction product of an alcohol with (meth)acrylonitrile, are contacted with hydrogen in the presence of a sponge cobalt catalyst. The improvement in the process resides in effecting the hydrogenation process utilizing a cyanoethylated alcohol feedstock contaminated with byproduct acrylonitrile and utilizing a solvent that solubilizes byproduct (meth)acrylonitrile present in the feedstock. Specific classes of solvents employed are ethers and amides.